HDAC11 and MRPS25

Data Source:
HPRD (two hybrid, in vitro)

		HDAC11	MRPS25
Description		histone deacetylase 11	mitochondrial ribosomal protein S25
Image		No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleus Plasma Membrane	Mitochondrion Mitochondrial Inner Membrane Ribosome
	Molecular Function	Histone Deacetylase Activity Protein Binding Transcription Factor Binding NAD-dependent Histone Deacetylase Activity (H3-K14 Specific)	Structural Constituent Of Ribosome
	Biological Process	Chromatin Organization Oligodendrocyte Development Histone Deacetylation Histone H3 Deacetylation	Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		NOTCH1 Intracellular Domain Regulates Transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Notch-HLH transcription pathway	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs		Belinostat Panobinostat
Diseases
GWAS		Body mass index ( 26426971) Height ( 20881960) Hip circumference adjusted for BMI ( 25673412) Ulcerative colitis ( 26278503)
Interacting Genes		7 interacting genes: CDC25A CDKN1A HDAC6 MAPK6 NELFCD NRM PHYHIP	1 interacting genes: ERCC6
Entrez ID		79885	64432
HPRD ID		09146	17594
Ensembl ID		ENSG00000163517	ENSG00000131368
Uniprot IDs		B5MCQ6 E7ETT9 Q6IA14 Q96DB2	P82663
PDB IDs			3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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