TUBA3C and XPO4

Data Source:
BioGRID (proximity labelling technology)

		TUBA3C	XPO4
Description		tubulin alpha 3c	exportin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule	Nuclear Pore Nucleoplasm Cytoplasm Cytosol
	Molecular Function	GTPase Activity Structural Constituent Of Cytoskeleton GTP Binding	Nuclear Export Signal Receptor Activity Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle	Protein Export From Nucleus Positive Regulation Of Protein Export From Nucleus
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) Recruitment of NuMA to mitotic centrosomes Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Cilium Assembly Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) Recruitment of NuMA to mitotic centrosomes Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Cilium Assembly Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins
Drugs
Diseases
GWAS		Coronary artery aneurysm in Kawasaki disease ( 27171184) Fasting blood insulin (BMI interaction) ( 22581228) Joint mobility (Beighton score) ( 27182965)	General cognitive ability ( 29844566) Neuroblastoma or malignant cutaneous melanoma ( 31605138) PR interval ( 30046033 32439900)
Interacting Genes		12 interacting genes: DYNLL1 DYNLT1 FYN GRM7 MYC NMI PFDN5 PXN SIAH1 TUBG1 UBC YWHAQ	3 interacting genes: EIF5A RAN UBQLN1
Entrez ID		7278	64328
HPRD ID		03958	18307
Ensembl ID		ENSG00000198033	ENSG00000132953
Uniprot IDs		P0DPH7 P0DPH8 Q1ZYQ1	Q9C0E2
PDB IDs
Enriched GO Terms of Interacting Partners?
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