TCF20 and TRAM1

Data Source:
BioGRID (biochemical)

		TCF20	TRAM1
Description		transcription factor 20	translocation associated membrane protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body	Endoplasmic Reticulum Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	DNA Binding RNA Binding Protein Binding Metal Ion Binding	Protein Binding Signaling Receptor Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Viral Process Protein Insertion Into ER Membrane
Pathways			SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Antisaccade task score ( 31596458) Arterial stiffness ( 31070453) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 29273807) Chronotype ( 30696823) Cognitive function ( 25644384) Intelligence ( 28530673) Isthmus-cingulate cortex volume ( 31530798) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656 30285260)	Cardiac Troponin-T levels ( 23247143) Erythrocyte cadmium concentration in never smokers ( 27005419) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		8 interacting genes: AR ESR1 H2AC20 H2BC21 JUN MAPK14 RNF4 SMAD1	12 interacting genes: APP CREB3 DRD2 ESR1 ESR2 GUCA2A SEC61B TICAM1 TIRAP TRAF6 UBC VKORC1
Entrez ID		6942	23471
HPRD ID		04378	05545
Ensembl ID		ENSG00000100207	ENSG00000067167
Uniprot IDs		Q9UGU0 W5ZR30	G3XAN4 Q15629 Q6FHL3
PDB IDs
Enriched GO Terms of Interacting Partners?
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