SUOX and MRPS35

Data Source:
BioGRID (affinity chromatography technology)

		SUOX	MRPS35
Description		sulfite oxidase	mitochondrial ribosomal protein S35
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix	Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit
	Molecular Function	Protein Binding Sulfite Oxidase Activity Heme Binding Molybdenum Ion Binding Molybdopterin Cofactor Binding	RNA Binding Structural Constituent Of Ribosome
	Biological Process	Sulfur Compound Metabolic Process Sulfide Oxidation, Using Sulfide:quinone Oxidoreductase	DNA Damage Response, Detection Of DNA Damage Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		Sulfide oxidation to sulfate	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs		{[2-Amino-4-oxo-6,7-di(sulfanyl-ÎºS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato(2-) phosphate}(dioxo)sulfanylmolybdenum
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Anorexia nervosa ( 28494655) Asthma ( 31959851 32296059 31619474) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Asthma or allergic disease (pleiotropy) ( 29785011) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Gastroesophageal reflux disease ( 31527586) Intelligence (MTAG) ( 29326435) Medication use (glucocorticoids) ( 31015401) Pediatric autoimmune diseases ( 26301688) Polycystic ovary syndrome ( 22885925) Refractive error ( 32231278) Type 1 diabetes ( 18198356 31152121) Vitiligo ( 22951725)	Type 2 diabetes ( 29632382) Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes		77 interacting genes: ACOT11 BAG4 C1D C5orf51 CAMK2A CCDC103 CDCA4 CEP76 COA7 COPS8 CRX CTAG1A CTAG1B CYB5R2 DMAP1 DUSP21 EIF3F ERICH4 EYA2 FAM217B FMNL2 FMR1 FNDC3B GOLGA6L9 HADHB HMG20A INCA1 ING5 ISCA2 ITGB3BP KIAA0753 KRT26 KRT27 KRT34 KRT40 LMO4 MAGEA11 MAGEB10 MBD3L1 MDFI MED28 MEIS3 MORN3 MYL7 MYO1B NUP62 PEX19 PIH1D2 POMC PRRX1 PTTG2 REL RELA RHOH RINT1 RPLP1 RSKR RUSC1 SERTAD3 SGTA SH3BP5L SNF8 SOHLH1 SPC24 STAT5B STH SYNGAP1 TEX12 TRIB3 TSC1 UBQLN2 UBR2 VBP1 VPS28 ZNF143 ZNF576 ZXDC
Entrez ID		6821	60488
HPRD ID		06055	11373
Ensembl ID		ENSG00000139531	ENSG00000061794
Uniprot IDs		A0A024RB79 P51687	P82673
PDB IDs		1MJ4	3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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