SUOX and KRT4

Data Source:
BioGRID (affinity chromatography technology, proximity labelling technology)

		SUOX	KRT4
Description		sulfite oxidase	keratin 4
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix	Nucleus Cytosol Intermediate Filament Cell Surface Keratin Filament Intermediate Filament Cytoskeleton
	Molecular Function	Protein Binding Sulfite Oxidase Activity Heme Binding Molybdenum Ion Binding Molybdopterin Cofactor Binding	Protein Binding
	Biological Process	Sulfur Compound Metabolic Process Sulfide Oxidation, Using Sulfide:quinone Oxidoreductase	Cytoskeleton Organization Epithelial Cell Differentiation Keratinization Negative Regulation Of Epithelial Cell Proliferation Cornification
Pathways		Sulfide oxidation to sulfate	Keratinization Formation of the cornified envelope
Drugs		{[2-Amino-4-oxo-6,7-di(sulfanyl-ÎºS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato(2-) phosphate}(dioxo)sulfanylmolybdenum
Diseases			White sponge nevus
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Anorexia nervosa ( 28494655) Asthma ( 31959851 32296059 31619474) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Asthma or allergic disease (pleiotropy) ( 29785011) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Gastroesophageal reflux disease ( 31527586) Intelligence (MTAG) ( 29326435) Medication use (glucocorticoids) ( 31015401) Pediatric autoimmune diseases ( 26301688) Polycystic ovary syndrome ( 22885925) Refractive error ( 32231278) Type 1 diabetes ( 18198356 31152121) Vitiligo ( 22951725)
Interacting Genes		77 interacting genes: ACOT11 BAG4 C1D C5orf51 CAMK2A CCDC103 CDCA4 CEP76 COA7 COPS8 CRX CTAG1A CTAG1B CYB5R2 DMAP1 DUSP21 EIF3F ERICH4 EYA2 FAM217B FMNL2 FMR1 FNDC3B GOLGA6L9 HADHB HMG20A INCA1 ING5 ISCA2 ITGB3BP KIAA0753 KRT26 KRT27 KRT34 KRT40 LMO4 MAGEA11 MAGEB10 MBD3L1 MDFI MED28 MEIS3 MORN3 MYL7 MYO1B NUP62 PEX19 PIH1D2 POMC PRRX1 PTTG2 REL RELA RHOH RINT1 RPLP1 RSKR RUSC1 SERTAD3 SGTA SH3BP5L SNF8 SOHLH1 SPC24 STAT5B STH SYNGAP1 TEX12 TRIB3 TSC1 UBQLN2 UBR2 VBP1 VPS28 ZNF143 ZNF576 ZXDC	21 interacting genes: C14orf119 CCDC57 CEP57 KRT13 KRT15 KRT16 KRT19 KRT24 KRT25 KRT27 KRT28 KRT31 KRT33B KRT35 KRT36 KRT37 KRT38 KRT40 PPP1R13B TRIM54 TUBGCP4
Entrez ID		6821	3851
HPRD ID		06055	00478
Ensembl ID		ENSG00000139531	ENSG00000170477
Uniprot IDs		A0A024RB79 P51687	P19013
PDB IDs		1MJ4
Enriched GO Terms of Interacting Partners?
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