STAT4 and NABP1

Data Source:
BioGRID (affinity chromatography technology)

		STAT4	NABP1
Description		signal transducer and activator of transcription 4	nucleic acid binding protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Cytosol	Chromosome, Telomeric Region Nucleus Nucleoplasm Cytosol Site Of Double-strand Break SOSS Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding	DNA Binding Single-stranded DNA Binding RNA Binding Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Defense Response Receptor Signaling Pathway Via JAK-STAT Cytokine-mediated Signaling Pathway Interleukin-12-mediated Signaling Pathway Interleukin-21-mediated Signaling Pathway Interleukin-23-mediated Signaling Pathway Regulation Of Cell Population Proliferation Response To Peptide Hormone Positive Regulation Of Transcription By RNA Polymerase II Interleukin-35-mediated Signaling Pathway	Double-strand Break Repair Via Homologous Recombination DNA Repair Cellular Response To DNA Damage Stimulus Mitotic Cell Cycle Checkpoint Response To Ionizing Radiation SnRNA Transcription By RNA Polymerase II Mitotic G2/M Transition Checkpoint
Pathways		Interleukin-20 family signaling Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation Interleukin-35 Signalling Interleukin-12 signaling Interleukin-12 signaling Interleukin-23 signaling Interleukin-21 signaling	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Arthritis (juvenile idiopathic) ( 33106285) Autoimmune thyroid disease ( 32581359) Autoimmune traits (pleiotropy) ( 30572963) Behcet's disease ( 23001997 23291587) Celiac disease ( 22057235 25920553 30572963) Celiac disease and Rheumatoid arthritis ( 26546613) Celiac disease or Rheumatoid arthritis ( 21383967) Eosinophil counts ( 32888494) Gamma glutamyl transferase levels ( 29403010) Generalized epilepsy ( 30531953) Hepatocellular carcinoma in hepatitis B infection ( 23242368) Idiopathic inflammatory myopathy ( 26362759) Inflammatory bowel disease ( 23128233) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Limited cutaneous systemic scleroderma ( 29293537) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757) Medication use (thyroid preparations) ( 31015401) Multiple sclerosis ( 31604244 24076602) Nontyphoidal Salmonella bacteraemia ( 29523850) Primary biliary cholangitis ( 28425483 23000144 21399635 26394269) Primary biliary cirrhosis ( 22961000) Rheumatoid arthritis ( 30423114 30572963 23143596 24390342 20453841 20453842) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) SjÃ¶gren's syndrome ( 24097066 24097067 28076899) Systemic lupus erythematosus ( 27399966 24871463 26606652 23273568 26663301 23053960 26316170 26502338 18204098 21408207 19165918 28714469 19838193 19838195) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic sclerosis ( 28314753 24387989 21750679 31672989 30572963 20383147 29293537 21779181) Systemic sclerosis (anti-centromere-positive) ( 29293537) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655) Vitiligo ( 27723757)	Colorectal cancer ( 23266556)
Interacting Genes		14 interacting genes: ADRB2 CREBBP CRK IL12RB1 IL12RB2 JUN MAP2K6 MAPK14 NMI PIAS2 SH2D1B STAT1 STAT3 ZNF467	10 interacting genes: COPS3 KHDRBS2 MKRN3 PURB QKI RBMX REL TFCP2 TP53 TRIM7
Entrez ID		6775	64859
HPRD ID		02779	08009
Ensembl ID		ENSG00000138378	ENSG00000173559
Uniprot IDs		Q14765	Q96AH0
PDB IDs
Enriched GO Terms of Interacting Partners?
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