SRP72 and EDN2

Data Source:
BioGRID (affinity chromatography technology)

		SRP72	EDN2
Description		signal recognition particle 72	endothelin 2
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Signal Recognition Particle	Extracellular Region Extracellular Space
	Molecular Function	RNA Binding Signal Recognition Particle Binding Protein Binding 7S RNA Binding TPR Domain Binding Ribosome Binding	Hormone Activity Endothelin B Receptor Binding
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane	Prostaglandin Biosynthetic Process Temperature Homeostasis Positive Regulation Of Leukocyte Chemotaxis Hormonal Regulation Of The Force Of Heart Contraction Positive Regulation Of The Force Of Heart Contraction By Chemical Signal Regulation Of Systemic Arterial Blood Pressure By Endothelin Cellular Calcium Ion Homeostasis Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Cell Population Proliferation Positive Regulation Of Heart Rate Artery Smooth Muscle Contraction Vein Smooth Muscle Contraction Cytokine-mediated Signaling Pathway Regulation Of Vasoconstriction Calcium-mediated Signaling Neutrophil Chemotaxis Macrophage Activation Vasoconstriction Positive Regulation Of Smooth Muscle Contraction Inositol Phosphate-mediated Signaling Macrophage Chemotaxis Lung Alveolus Development Positive Regulation Of Prostaglandin-endoperoxide Synthase Activity Energy Homeostasis
Pathways		SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane	Peptide ligand-binding receptors G alpha (q) signalling events
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378)	Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Phenylephrine infusion rate during anesthesia ( 31455332) PR interval ( 32439900) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		10 interacting genes: CASP3 CASP6 CDC42 FCHSD2 HSPB1 PYGM SKIL SRP68 SULT2B1 TULP3	3 interacting genes: CMA1 KEL MME
Entrez ID		6731	1907
HPRD ID		03671	07173
Ensembl ID		ENSG00000174780	ENSG00000127129
Uniprot IDs		O76094 V9HWK0	P20800
PDB IDs		5M72 5M73 5WRV 5WRW
Enriched GO Terms of Interacting Partners?
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