SRP19 and ATG12

Data Source:
BioGRID (affinity chromatography technology)

		SRP19	ATG12
Description		signal recognition particle 19	autophagy related 12
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GO Annotations	Cellular Component	Nucleolus Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Signal Recognition Particle	Autophagosome Cytosol Phagocytic Vesicle Membrane Phagophore Assembly Site Membrane Atg12-Atg5-Atg16 Complex
	Molecular Function	RNA Binding Protein Binding 7S RNA Binding Ribosome Binding	Protein Binding
	Biological Process	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition	Autophagosome Assembly Autophagy Of Mitochondrion C-terminal Protein Lipidation Viral Process Macroautophagy Autophagy Of Nucleus
Pathways		SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane	Macroautophagy Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS
Interacting Genes		8 interacting genes: APP IPO5 IPO7 IPO8 KPNA1 MAPK8IP2 SRP54 TNPO1	15 interacting genes: APP ATG10 ATG3 ATG5 ATG7 CRX DOCK9 IER2 KRTAP4-12 MDFI MEOX2 PLSCR1 PTK2 SERTAD1 SERTAD2
Entrez ID		6728	9140
HPRD ID		01644	08496
Ensembl ID		ENSG00000153037	ENSG00000145782
Uniprot IDs		A0A087WYR0 A0A2U3TZN1 P09132	O94817
PDB IDs		1JID 1MFQ 1RY1 2J37 3KTV 4P3E 5M73	4GDK 4GDL 4NAW
Enriched GO Terms of Interacting Partners?
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