KLHL25 and SEC11A

Data Source:
BioGRID (proximity labelling technology)

		KLHL25	SEC11A
Description		kelch like family member 25	SEC11 homolog A, signal peptidase complex subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cul3-RING Ubiquitin Ligase Complex	Signal Peptidase Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function		Serine-type Endopeptidase Activity Protein Binding Peptidase Activity
	Biological Process	Regulation Of Translational Initiation Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Post-translational Protein Modification	Signal Peptide Processing
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	SRP-dependent cotranslational protein targeting to membrane Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Synthesis, secretion, and deacylation of Ghrelin
Drugs
Diseases
GWAS		Adverse response to chemotherapy in breast cancer (alopecia) (anti-microtubule) ( 24025145) Adverse response to chemotherapy in breast cancer (alopecia) (docetaxel) ( 24025145) Aging traits ( 17903295) Birth weight ( 31043758) Idiopathic pulmonary fibrosis ( 29066090) Offspring birth weight ( 31043758) Psychosis (methamphetamine induced) ( 23594818) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Response to ketamine in bipolar disorder or major depression (antidepressant effects) ( 30552317) Schizophrenia ( 29483656)
Interacting Genes		1 interacting genes: ACLY	5 interacting genes: ADAM33 BCHE CSNK2B NUPR1 SLC35F6
Entrez ID		64410	23478
HPRD ID		07780	07503
Ensembl ID		ENSG00000183655	ENSG00000140612
Uniprot IDs		Q9H0H3	A0A024RC78 H0YKT4 P67812
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?