SELENOP and MKKS

Data Source:
BioGRID (affinity chromatography technology)

		SELENOP	MKKS
Description		selenoprotein P	McKusick-Kaufman syndrome
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Platelet Dense Granule Lumen Extracellular Exosome	Nucleus Cytoplasm Centrosome Cytosol Motile Cilium Kinociliary Basal Body
	Molecular Function	Selenium Binding	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding ATP Binding Unfolded Protein Binding
	Biological Process	Selenium Compound Metabolic Process Platelet Degranulation Response To Oxidative Stress	Heart Looping Protein Folding Spermatid Development Determination Of Left/right Symmetry Heart Development Visual Perception Sensory Perception Of Smell Gonad Development Negative Regulation Of Gene Expression Artery Smooth Muscle Contraction Striatum Development Hippocampus Development Cerebral Cortex Development Negative Regulation Of Actin Filament Polymerization Melanosome Transport Developmental Process Negative Regulation Of GTPase Activity Social Behavior Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Positive Regulation Of Multicellular Organism Growth Vasodilation Fat Cell Differentiation Photoreceptor Cell Maintenance Negative Regulation Of Blood Pressure Intracellular Transport Brain Morphogenesis Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Chaperone-mediated Protein Complex Assembly Cartilage Development Regulation Of Stress Fiber Assembly Pigment Granule Aggregation In Cell Center Convergent Extension Involved In Gastrulation Cilium Assembly Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Face Development Non-motile Cilium Assembly
Pathways		Platelet degranulation	BBSome-mediated cargo-targeting to cilium
Drugs		Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases			46,XX disorders of sex development (Other), including: Mullerian aplasia and hyperandrogenism; McKusick-Kaufman syndrome Bardet-Biedl syndrome (BBS)
GWAS
Interacting Genes		4 interacting genes: EGFR EP300 MEOX2 THRA	4 interacting genes: APP CDR2 PTN ZBED1
Entrez ID		6414	8195
HPRD ID		03286	05356
Ensembl ID		ENSG00000250722	ENSG00000125863
Uniprot IDs		P49908	B7Z3W9 Q9NPJ1
PDB IDs
Enriched GO Terms of Interacting Partners?
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