EPB41L4A and DCP2

Data Source:
BioGRID (affinity chromatography technology)

		EPB41L4A	DCP2
Description		erythrocyte membrane protein band 4.1 like 4A	decapping mRNA 2
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Cytoskeleton	P-body Nucleoplasm Cytoplasm Cytosol RISC Complex Cell Junction Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Molecular_function Cytoskeletal Protein Binding	5'-3' Exoribonuclease Activity Protein Binding Exoribonuclease Activity, Producing 5'-phosphomonoesters Manganese Ion Binding M7G(5')pppN Diphosphatase Activity Telomerase RNA Binding
	Biological Process	Biological_process Actomyosin Structure Organization	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA MRNA Catabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Regulation Of MRNA Stability Exonucleolytic Catabolism Of Deadenylated MRNA Histone MRNA Catabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Regulation Of Telomerase RNA Localization To Cajal Body
Pathways			ATF4 activates genes in response to endoplasmic reticulum stress mRNA decay by 5' to 3' exoribonuclease Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA KSRP (KHSRP) binds and destabilizes mRNA
Drugs
Diseases
GWAS		Common carotid intima-media thickness in HIV negative individuals ( 29206233) Night sleep phenotypes ( 27126917) Refractive error ( 32231278) Suicide ideation score in major depressive disorder ( 26079190) Thyroid cancer ( 28195142) vWF and FVIII levels ( 21810271)	Worry/vulnerability (special factor of neuroticism) ( 30867560)
Interacting Genes		5 interacting genes: APP MIB1 SRPK1 SRPK2 TNS2	12 interacting genes: AGO1 AGO2 DCP1A DCP1B MIR15B MTOR NAGK POLA2 PSMB1 TRIM21 UPF1 UPF2
Entrez ID		64097	167227
HPRD ID		09939	13125
Ensembl ID		ENSG00000129595	ENSG00000172795
Uniprot IDs		Q8N8X1 Q8NEH8 Q9HCS5	Q8IU60
PDB IDs			5MP0 5QOH 5QOI 5QOJ 5QOK 5QOL 5QOM 5QON 5QOO 5QOP 5QOQ 5QOR 5QOS 5QOT 5QOU 5QOV 5QOW 5QOX 5QOY 5QOZ 5QP0 5QP1 5QP2 5QP3 5QP4 5QP5 5QP6 5QP7 5QP8 5QP9 5QPA 5QPB 5QPC
Enriched GO Terms of Interacting Partners?
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