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CCL22 and NLGN4X
Data Source:
BioGRID
(two hybrid)
CCL22
NLGN4X
Description
C-C motif chemokine ligand 22
neuroligin 4 X-linked
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Plasma Membrane
Integral Component Of Plasma Membrane
Cell Surface
Integral Component Of Membrane
Dendrite
Synapse
Excitatory Synapse
Spanning Component Of Membrane
Presynapse
Postsynaptic Density Membrane
Symmetric, GABA-ergic, Inhibitory Synapse
Asymmetric, Glutamatergic, Excitatory Synapse
Molecular Function
Protein Binding
Chemokine Activity
CCR Chemokine Receptor Binding
Protein Binding
Chloride Ion Binding
Signaling Receptor Activity
Neurexin Family Protein Binding
Protein Homodimerization Activity
Cell Adhesion Molecule Binding
Scaffold Protein Binding
Biological Process
Monocyte Chemotaxis
Chemotaxis
Inflammatory Response
Immune Response
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
Response To Virus
Cytokine-mediated Signaling Pathway
Neutrophil Chemotaxis
Positive Regulation Of GTPase Activity
Lymphocyte Chemotaxis
Chemokine-mediated Signaling Pathway
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Interferon-gamma
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Brainstem Development
Neuron Cell-cell Adhesion
Chemical Synaptic Transmission
Learning
Cerebellum Development
Neuron Differentiation
Adult Behavior
Social Behavior
Organ Growth
Cell-cell Junction Organization
Synaptic Vesicle Endocytosis
Modulation Of Chemical Synaptic Transmission
Synapse Organization
Vocalization Behavior
Negative Regulation Of Excitatory Postsynaptic Potential
Postsynaptic Membrane Assembly
Presynaptic Membrane Assembly
Presynapse Assembly
Pathways
Chemokine receptors bind chemokines
Interleukin-10 signaling
Interleukin-4 and Interleukin-13 signaling
Neurexins and neuroligins
Neurexins and neuroligins
Drugs
Diseases
Non-syndromic X-linked mental retardation
GWAS
Asthma (
32296059
)
Blood protein levels (
30072576
29875488
)
Multiple sclerosis (
24076602
)
Systemic lupus erythematosus (
28714469
)
Metabolite levels (
23823483
)
Schizophrenia (
25056061
29483656
)
Interacting Genes
10 interacting genes:
AQP6
CCL14
CCL19
CCR4
CRYAB
DPP4
GCLC
HERC3
PF4V1
VCAM1
2 interacting genes:
DLG4
DLGAP2
Entrez ID
6367
57502
HPRD ID
04263
02336
Ensembl ID
ENSG00000102962
ENSG00000146938
Uniprot IDs
O00626
A0A024RBV0
A8K4S1
B3KP11
Q8N0W4
PDB IDs
2WQZ
2XB6
3BE8
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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