S100A7 and PITRM1

Data Source:
BioGRID (affinity chromatography technology)

		S100A7	PITRM1
Description		S100 calcium binding protein A7	pitrilysin metallopeptidase 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Focal Adhesion Azurophil Granule Lumen Collagen-containing Extracellular Matrix	Mitochondrion Mitochondrial Matrix
	Molecular Function	Calcium Ion Binding Protein Binding Zinc Ion Binding Calcium-dependent Protein Binding RAGE Receptor Binding	Metalloendopeptidase Activity Enzyme Activator Activity Metallopeptidase Activity Zinc Ion Binding
	Biological Process	Response To Reactive Oxygen Species Angiogenesis Epidermis Development Positive Regulation Of T Cell Chemotaxis Antimicrobial Humoral Response Keratinocyte Differentiation Response To Lipopolysaccharide Neutrophil Degranulation Innate Immune Response Defense Response To Gram-negative Bacterium Sequestering Of Metal Ion Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Granulocyte Chemotaxis Positive Regulation Of Monocyte Chemotaxis	Proteolysis Protein Targeting To Mitochondrion Protein Processing Regulation Of Catalytic Activity
Pathways		Neutrophil degranulation Metal sequestration by antimicrobial proteins	Mitochondrial protein import
Drugs		Ibuprofen Zinc 8-anilinonaphthalene-1-sulfonic acid Dexibuprofen Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Blood protein levels ( 30072576)	Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Metabolite levels ( 23823483) Scalp hair shape ( 26926045)
Interacting Genes		8 interacting genes: CLVS2 COPS5 EGFR FABP5 RANBP9 S100A7L2 TGM2 UCHL5
Entrez ID		6278	10531
HPRD ID		02645	07142
Ensembl ID		ENSG00000143556	ENSG00000107959
Uniprot IDs		P31151	Q5JRX3
PDB IDs		1PSR 2PSR 2WND 2WOR 2WOS 3PSR 4AQJ	4L3T 4NGE 4RPU
Enriched GO Terms of Interacting Partners?
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