RRM2 and LPIN1

Data Source:
BioGRID (two hybrid)

		RRM2	LPIN1
Description		ribonucleotide reductase regulatory subunit M2	lipin 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Mitochondrial Outer Membrane Endoplasmic Reticulum Membrane Cytosol Nuclear Membrane
	Molecular Function	Ribonucleoside-diphosphate Reductase Activity, Thioredoxin Disulfide As Acceptor Protein Binding Metal Ion Binding	Transcription Coactivator Activity Protein Binding Phosphatidate Phosphatase Activity
	Biological Process	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle DNA Replication Deoxyribonucleotide Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Negative Regulation Of G0 To G1 Transition	Triglyceride Mobilization Phosphatidylethanolamine Biosynthetic Process Phosphatidylcholine Biosynthetic Process Mitotic Nuclear Envelope Disassembly Fatty Acid Catabolic Process Dephosphorylation Triglyceride Biosynthetic Process Animal Organ Regeneration Cellular Response To Insulin Stimulus Cellular Lipid Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cold-induced Thermogenesis
Pathways		Interconversion of nucleotide di- and triphosphates G1/S-Specific Transcription Transcriptional Regulation by E2F6	Synthesis of PC Synthesis of PE Depolymerisation of the Nuclear Lamina Triglyceride biosynthesis
Drugs		Cladribine Imexon Gallium nitrate Motexafin gadolinium GTI 2040
Diseases
GWAS		Kidney function decline traits ( 25493955) Prostate cancer ( 23535732)	Chronotype ( 30696823) Metabolite levels ( 23823483) Post bronchodilator percent predicted FEV1 in smoking ( 30068317)
Interacting Genes		9 interacting genes: CDH1 CDK1 DNM1L KAT5 PLK3 RRM1 RRM2B SDCBP TP53	1 interacting genes: CDK6
Entrez ID		6241	23175
HPRD ID		01587	09271
Ensembl ID		ENSG00000171848	ENSG00000134324
Uniprot IDs		P31350	Q14693
PDB IDs		2UW2 3OLJ 3VPM 3VPN 3VPO
Enriched GO Terms of Interacting Partners?
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