RPL27A and PTGES2

Data Source:
BioGRID (two hybrid)

		RPL27A	PTGES2
Description		ribosomal protein L27a	prostaglandin E synthase 2
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Cytosol Membrane Cytosolic Large Ribosomal Subunit	Golgi Membrane Extracellular Region Nucleus Mitochondrion Cytosol Integral Component Of Membrane Azurophil Granule Lumen Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	DNA Binding Protein Binding Protein Disulfide Oxidoreductase Activity Lyase Activity Heme Binding Glutathione Binding Prostaglandin-E Synthase Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	Lipid Metabolic Process Glutathione Metabolic Process Cyclooxygenase Pathway Neutrophil Degranulation Positive Regulation Of Transcription, DNA-templated
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Neutrophil degranulation
Drugs
Diseases			Penile cancer
GWAS		Body mass index ( 26426971 20935630 28448500) Body mass index (age <50) ( 26426971) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body mass index x sex x age interaction (4df test) ( 26426971) Fruit consumption ( 32066663) Obesity ( 23563607)	Body mass index ( 26426971)
Interacting Genes		6 interacting genes: DUX4 GTF2F2 PEX6 PRKACB PTEN SIAH1	5 interacting genes: ADRB2 C1orf189 CEBPB EXOSC10 PTGFR
Entrez ID		6157	80142
HPRD ID		04701	07458
Ensembl ID		ENSG00000166441	ENSG00000148334
Uniprot IDs		P46776	A6NHH0 B3KPZ2 B4DWP1 Q9H7Z7
PDB IDs		4BXF 4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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