PTPRZ1 and NMB

Data Source:
HPRD (in vivo)

		PTPRZ1	NMB
Description		protein tyrosine phosphatase receptor type Z1	neuromedin B
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GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Intrinsic Component Of Plasma Membrane	Extracellular Region Neuron Projection
	Molecular Function	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Integrin Binding Protein Binding	Hormone Activity Neuropeptide Hormone Activity Protein Binding Neuromedin B Receptor Binding
	Biological Process	Protein Dephosphorylation Central Nervous System Development Learning Or Memory Cytokine-mediated Signaling Pathway Regulation Of Myelination Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Neuron Apoptotic Process Oligodendrocyte Differentiation Positive Regulation Of Oligodendrocyte Differentiation Regulation Of Oligodendrocyte Progenitor Proliferation	Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Glucose Homeostasis Positive Regulation Of Hormone Secretion Negative Regulation Of Hormone Secretion Arachidonic Acid Secretion
Pathways		Other interleukin signaling	Peptide ligand-binding receptors G alpha (q) signalling events
Drugs
Diseases
GWAS		Hand grip strength ( 27325353) Heel bone mineral density ( 30598549) Lung adenocarcinoma ( 28604730)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Creatine kinase levels ( 29403010) P wave terminal force ( 28794112) Schizophrenia ( 29483656)
Interacting Genes		13 interacting genes: ADD2 ALK ARHGAP35 CTNNB1 FYN GIT1 HMGB1 IL34 MDK MGAT5B PTN PTPRF TNR	4 interacting genes: BIRC2 GADD45G NMBR TPP1
Entrez ID		5803	4828
HPRD ID		01481	01210
Ensembl ID		ENSG00000106278	ENSG00000197696
Uniprot IDs		B4DFE7 P23471	P08949
PDB IDs		3JXF 3S97 5AWX 5H08	1C98 1C9A
Enriched GO Terms of Interacting Partners?
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