RPTOR and TNRC6C

  • Data Source:
  • BioGRID (affinity chromatography technology)

RPTOR

TNRC6C

Description regulatory associated protein of MTOR complex 1 trinucleotide repeat containing adaptor 6C
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Airway responsiveness in chronic obstructive pulmonary disease ( 25514360)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Bipolar disorder ( 31043756)
  • Body mass index ( 28892062 25673413)
  • Body size at age 10 ( 32376654)
  • Hypertension ( 30487518)
  • Mean arterial pressure ( 30487518)
  • NASH resolution in nonalcoholic steatohepatitis ( 31832568)
  • Nicotine dependence symptom count ( 25555482)
  • Obesity ( 23563607)
  • Pulse pressure ( 29403010 30487518)
  • Systolic blood pressure ( 30487518)
  • Normal facial asymmetry (angle of deformation score) ( 30631343)
  • Refractive error ( 32231278)
  • Serum uric acid levels ( 29559957)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
  • Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes 23 interacting genes: CILK1 DUXAP9 EIF4EBP1 EIF4EBP2 IRS1 IRS2 LINC00839 MAPK1 MAPK3 MARK4 MLST8 MTOR NRBF2 PLD2 PRKAA1 PRKAA2 RAP1B RHEB RPS6KA1 RPS6KB1 RRAGA RRAGB WIPI2 2 interacting genes: AGO4 UBC
Entrez ID 57521 57690
HPRD ID 06184 10026
Ensembl ID ENSG00000141564 ENSG00000078687
Uniprot IDs Q6DKI0 Q8N122 Q9HCJ0
PDB IDs 5H64 6BCU 6BCX 6SB0 6SB2 6U62 2DKL 2X04 3KTP
Enriched GO Terms of Interacting Partners?
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