STARD9 and TTBK2

Data Source:
BioGRID (affinity chromatography technology)

		STARD9	TTBK2
Description		StAR related lipid transfer domain containing 9	tau tubulin kinase 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centriole	Extracellular Space Nucleus Cytoplasm Centriole Cytosol Ciliary Transition Zone Ciliary Basal Body
	Molecular Function	Microtubule Motor Activity ATP Binding Microtubule Binding Lipid Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinesin Binding Tau Protein Binding Tau-protein Kinase Activity Microtubule Plus-end Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Microtubule-based Movement Spindle Assembly	Microtubule Cytoskeleton Organization Negative Regulation Of Microtubule Depolymerization Smoothened Signaling Pathway Peptidyl-serine Phosphorylation Cerebellum Development Cerebellar Granular Layer Development Cerebellar Granule Cell Precursor Tangential Migration Regulation Of Cell Migration Cilium Assembly Ciliary Basal Body-plasma Membrane Docking Negative Regulation Of Protein Localization To Microtubule Negative Regulation Of Microtubule Binding
Pathways			Anchoring of the basal body to the plasma membrane
Drugs
Diseases			Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		Bipolar disorder ( 31043756) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Glucose homeostasis traits ( 25524916) MGMT methylation in smokers ( 26183928)	Bipolar disorder ( 31043756) Hematocrit ( 32888494) MGMT methylation in smokers ( 26183928)
Interacting Genes		5 interacting genes: CDK5RAP2 HERPUD1 NDUFA7 PPP1CC SVIL	1 interacting genes: KLHL12
Entrez ID		57519	146057
HPRD ID		15442	10288
Ensembl ID		ENSG00000159433	ENSG00000128881
Uniprot IDs		Q9P2P6	Q6IQ55 Q8IWY7
PDB IDs			6U0K 6VRF
Enriched GO Terms of Interacting Partners?
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