SLC12A5 and L3MBTL1

Data Source:
BioGRID (proximity labelling technology)

		SLC12A5	L3MBTL1
Description		solute carrier family 12 member 5	L3MBTL histone methyl-lysine binding protein 1
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Neuron Projection Neuronal Cell Body Synapse Cell Periphery	Chromatin Condensed Chromosome Nucleus Nucleoplasm Nucleolus Plasma Membrane
	Molecular Function	Chloride Transmembrane Transporter Activity Potassium:chloride Symporter Activity	Chromatin Binding Protein Binding Zinc Ion Binding Nucleosome Binding Nucleosomal Histone Binding SAM Domain Binding Methylated Histone Binding Histone Binding Identical Protein Binding
	Biological Process	Ion Transport Cellular Ion Homeostasis Cell Volume Homeostasis Hypotonic Response Chemical Synaptic Transmission Learning Cellular Chloride Ion Homeostasis Multicellular Organism Growth Thermosensory Behavior Response To Drug Chloride Ion Homeostasis Potassium Ion Homeostasis Dendritic Spine Development Chloride Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Chromatin Organization Regulation Of Mitotic Nuclear Division Hemopoiesis Regulation Of Megakaryocyte Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Cation-coupled Chloride cotransporters	Regulation of TP53 Activity through Methylation
Drugs		Potassium chloride Bumetanide	2-(N-morpholino)ethanesulfonic acid
Diseases
GWAS		Chronotype ( 30696823) Crohn's disease ( 28067908) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 28067908) Reticulocyte count ( 32888494) Systemic sclerosis ( 29293537) Triglyceride levels ( 32154731)	Antibody level in response to infection ( 25758998) Daytime sleep phenotypes ( 27126917)
Interacting Genes		2 interacting genes: CCR4 F2RL1	7 interacting genes: CBX3 ETV6 ETV7 H1-5 H4-16 RB1 SETD7
Entrez ID		57468	26013
HPRD ID		09469	16387
Ensembl ID		ENSG00000124140	ENSG00000185513
Uniprot IDs		Q9H2X9	Q9Y468
PDB IDs		6M23	1OYX 1OZ2 1OZ3 2PQW 2RHI 2RHU 2RHX 2RHY 2RHZ 2RI2 2RI3 2RI5 2RJC 2RJD 2RJE 2RJF 3OQ5 3P8H 3UWN 6BYB
Enriched GO Terms of Interacting Partners?
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