UBAP2 and GBA2

Data Source:
BioGRID (biochemical)

		UBAP2	GBA2
Description		ubiquitin associated protein 2	glucosylceramidase beta 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm	Smooth Endoplasmic Reticulum Cytosol Plasma Membrane Integral Component Of Membrane Extrinsic Component Of Membrane Extrinsic Component Of Endoplasmic Reticulum Membrane Extrinsic Component Of Golgi Membrane
	Molecular Function	RNA Binding Protein Binding Cadherin Binding	Glucosylceramidase Activity Beta-glucosidase Activity Glucosyltransferase Activity Steryl-beta-glucosidase Activity
	Biological Process	Negative Regulation Of Gene Expression Positive Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT	Carbohydrate Metabolic Process Glucosylceramide Catabolic Process Glycosphingolipid Metabolic Process Central Nervous System Development Cholesterol Metabolic Process Bile Acid Metabolic Process Glycoside Catabolic Process Central Nervous System Neuron Development Lipid Glycosylation Regulation Of Actin Filament Polymerization Regulation Of Microtubule Polymerization Regulation Of Membrane Lipid Distribution
Pathways			Glycosphingolipid metabolism
Drugs
Diseases
GWAS		Adult body size ( 32376654) Bipolar disorder ( 20351715) Estimated glomerular filtration rate ( 31152163) Heel bone mineral density ( 30598549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Lymphocyte counts ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Mosquito bite size ( 28199695) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Type 2 diabetes ( 30054458 30297969)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		43 interacting genes: ASB13 ATPAF2 BANP C10orf55 CREM DAZAP2 EFHC1 FAM168B FNDC3B FOXH1 HGS IGFN1 ISX ITCH JMJD7 KANK2 KRTAP15-1 LCK MGAT5B NOXA1 NPAS2 NUTF2 OTX1 PLAC8 PLEKHB2 PPP2CA PRSS53 PSMB8 RBPMS RHOXF2 SHC3 SPAG8 TENT5B TEP1 TEX37 TFG TLE5 TP53BP1 TRAPPC6A VENTX VPS37C WRAP53 ZNF34	2 interacting genes: APP MTNR1A
Entrez ID		55833	57704
HPRD ID		06748	13569
Ensembl ID		ENSG00000137073	ENSG00000070610
Uniprot IDs		B4DH66 B7Z7P2 Q5T6F2 Q9P0H6	Q9HCG7
PDB IDs
Enriched GO Terms of Interacting Partners?
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