ENOX1 and AKAP11

Data Source:
BioGRID (biochemical, affinity chromatography technology, biochemical)

		ENOX1	AKAP11
Description		ecto-NOX disulfide-thiol exchanger 1	A-kinase anchoring protein 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane External Side Of Plasma Membrane	Nucleolus Cytoplasm Peroxisome Microtubule Organizing Center Cytosol Plasma Membrane
	Molecular Function	Nucleic Acid Binding Protein Binding Oxidoreductase Activity	Protein Binding Protein Phosphatase 1 Binding Kinase Regulator Activity Protein Kinase A Regulatory Subunit Binding Protein Kinase A Binding
	Biological Process	Ultradian Rhythm	Renal Water Homeostasis Protein Localization Cortical Actin Cytoskeleton Organization Intracellular Signal Transduction Protein Localization To Endosome Regulation Of Kinase Activity
Pathways
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) End-stage coagulation ( 23381943) Major depressive disorder ( 23377640) Mercury levels ( 26025379) Parent of origin effect on receptive language ability (paternal) ( 32635940) Photic sneeze reflex ( 27182965) Response to cognitive-behavioural therapy in anxiety and major depressive disorders ( 31123309) Response to tocilizumab in rheumatoid arthritis ( 22491018)	Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic rhinitis ( 30013184) Asthma (childhood onset) ( 30929738) Bone mineral density ( 24249740) Bone mineral density (spine) ( 19801982) Crohn's disease ( 28067908) Hepcidin levels ( 27846281) Inflammatory bowel disease ( 28067908) Lumbar spine bone mineral density ( 29499414 22504420) Lumbar spine bone mineral density (integral) ( 27476799) Lumbar spine bone mineral density (trabecular) ( 27476799) Medication use (drugs affecting bone structure and mineralization) ( 31015401) Medication use (thyroid preparations) ( 31015401) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		11 interacting genes: EEF1G EIF6 ENOX2 GORASP2 LNX1 NIF3L1 SDCBP SULT1E1 TRIM43 ZBTB16 ZMYND19	6 interacting genes: GSK3B PPP1CA PPP1CC PRKAR1A PRKAR2A PRKAR2B
Entrez ID		55068	11215
HPRD ID		07644	05261
Ensembl ID		ENSG00000120658	ENSG00000023516
Uniprot IDs		A0A024RDT8 A0A024RDX6 Q8TC92	Q9UKA4
PDB IDs
Enriched GO Terms of Interacting Partners?
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