OTUD4 and DNAAF5

Data Source:
BioGRID (affinity chromatography technology)

		OTUD4	DNAAF5
Description		OTU deubiquitinase 4	dynein axonemal assembly factor 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Cytoplasm Motile Cilium
	Molecular Function	RNA Binding Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Molecular Adaptor Activity Lys63-specific Deubiquitinase Activity	Dynein Intermediate Chain Binding
	Biological Process	Protein Deubiquitination Protein Phosphopantetheinylation Negative Regulation Of Toll-like Receptor Signaling Pathway Innate Immune Response Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Positive Regulation Of DNA Demethylation Regulation Of Protein K48-linked Deubiquitination Negative Regulation Of Interleukin-1-mediated Signaling Pathway	Cilium Movement Outer Dynein Arm Assembly Inner Dynein Arm Assembly
Pathways
Drugs
Diseases
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Heel bone mineral density ( 30598549 28869591) Height ( 28552196) Hip circumference adjusted for BMI ( 25673412) Lung function (FEV1) ( 30061609) Malaria ( 31844061) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 31628463) Red blood cell count ( 32888494) Refractive error ( 32231278) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 27863252) Subcortical volume (MOSTest) ( 32665545)	Cerebrospinal P-tau181p levels ( 28247064) Initial pursuit acceleration ( 29064472)
Interacting Genes		10 interacting genes: ALKBH3 EXOSC8 MAVS REL STAT1 TCF4 UBC USP7 VDR ZNF655	2 interacting genes: FEZ1 ZBTB16
Entrez ID		54726	54919
HPRD ID		11033	07903
Ensembl ID		ENSG00000164164	ENSG00000164818
Uniprot IDs		Q01804	B3KPE2 Q86Y56
PDB IDs
Enriched GO Terms of Interacting Partners?
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