POU3F2 and LGALS13

Data Source:
BioGRID (affinity chromatography technology)

		POU3F2	LGALS13
Description		POU class 3 homeobox 2	galectin 13
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Transcription Regulator Complex	Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific Double-stranded DNA Binding	Lysophospholipase Activity Protein Binding Carbohydrate Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Nervous System Development Positive Regulation Of Cell Population Proliferation Epidermis Development Negative Regulation Of Gene Expression Astrocyte Development Cerebral Cortex Radially Oriented Cell Migration Forebrain Ventricular Zone Progenitor Cell Division Hypothalamus Cell Differentiation Neurohypophysis Development Myelination In Peripheral Nervous System Neuron Differentiation Positive Regulation Of Multicellular Organism Growth Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Neuron Fate Commitment Neuron Fate Specification Neuron Development Regulation Of Axonogenesis Cellular Response To Organic Substance	Phospholipid Metabolic Process Apoptotic Process Positive Regulation Of T Cell Apoptotic Process
Pathways		EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
GWAS		Bipolar disorder ( 24618891 27329760) Body size at age 10 ( 32376654) Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125) Chronotype ( 30696823) Educational attainment ( 25201988) Erectile dysfunction ( 30583798) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels ( 32203549) Intelligence ( 28530673) Metabolite levels ( 23823483) Morning person ( 30696823) Number of sexual partners ( 30643258) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965) QT interval (drug interaction) ( 23459443) Regular attendance at a religious group ( 29970889) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258)	Lead levels ( 26025379)
Interacting Genes		11 interacting genes: EP300 GTF2B NFYA NFYB NFYC PAX3 POU3F4 PQBP1 SOX10 SOX11 TBP	10 interacting genes: ACTB ACTG1 ANXA2 CREB5 HOXA1 NUFIP2 OTX1 PACSIN3 PHLDA1 POU4F2
Entrez ID		5454	29124
HPRD ID		02734	16375
Ensembl ID		ENSG00000184486	ENSG00000105198
Uniprot IDs		P20265	Q9UHV8
PDB IDs			1F87 5XG7 5XG8 5Y03 6A62 6A63 6A64 6A65 6A66 6KJW 6KJX 6KJY
Enriched GO Terms of Interacting Partners?
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