SEPTIN5 and PRODH

Data Source:
BioGRID (biochemical)

		SEPTIN5	PRODH
Description		septin 5	proline dehydrogenase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Septin Ring Synaptic Vesicle Microtubule Cytoskeleton Septin Complex Cell Division Site	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Intracellular Membrane-bounded Organelle
	Molecular Function	GTPase Activity Structural Molecule Activity Protein Binding GTP Binding Identical Protein Binding Molecular Adaptor Activity	Proline Dehydrogenase Activity FAD Binding
	Biological Process	Synaptic Vesicle Targeting Regulation Of Exocytosis Adult Behavior Cellular Protein Localization Social Behavior Cytoskeleton-dependent Cytokinesis Regulation Of Synaptic Vesicle Exocytosis	Proline Metabolic Process Proline Catabolic Process Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Proline Catabolic Process To Glutamate Positive Regulation Of Cell Death 4-hydroxyproline Catabolic Process
Pathways			Proline catabolism
Drugs			Proline
Diseases			Hyperprolinemia (HP)
GWAS			Amino acid levels ( 26068415) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Metabolic traits ( 21886157) Metabolite levels ( 31628463) Neutrophil count ( 32888494) Plasma free amino acid levels (adjusted for one other PFAA) ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Plasma free proline levels ( 30659259) Platelet count ( 32888494) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 25569235) White blood cell count ( 32888494)
Interacting Genes		23 interacting genes: APP CDK5R1 DDIT4L KAT7 KIDINS220 LSM8 MAGEA2 MAGEA2B MAPK6 MYOG PFN2 PLEKHF2 PRKN SEPTIN1 SEPTIN11 SEPTIN12 SEPTIN2 SEPTIN4 SEPTIN7 SEPTIN8 SPG21 STX1A STX4
Entrez ID		5413	5625
HPRD ID		04100	08433
Ensembl ID		ENSG00000184702	ENSG00000100033
Uniprot IDs		Q99719 X5DNA9	O43272
PDB IDs
Enriched GO Terms of Interacting Partners?
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