RAB8B and VPS13C

Data Source:
HPRD (in vivo, in vitro)

		RAB8B	VPS13C
Description		RAB8B, member RAS oncogene family	vacuolar protein sorting 13 homolog C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endosome Peroxisomal Membrane Plasma Membrane Synaptic Vesicle Nuclear Body Trans-Golgi Network Transport Vesicle Phagocytic Vesicle Membrane Intracellular Membrane-bounded Organelle Phagocytic Vesicle Perinuclear Region Of Cytoplasm Cell Tip Recycling Endosome Membrane Extracellular Exosome	Cytoplasm Mitochondrial Outer Membrane Cytosol Extrinsic Component Of Membrane Dense Core Granule Membrane Extracellular Exosome
	Molecular Function	GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding GDP Binding TPR Domain Binding
	Biological Process	Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Antigen Processing And Presentation Positive Regulation Of Cell Projection Organization Cellular Response To Insulin Stimulus Protein Import Into Peroxisome Membrane Golgi Vesicle Fusion To Target Membrane Positive Regulation Of Corticotropin Secretion Cilium Assembly Protein Localization To Plasma Membrane Cell-substrate Junction Organization	Protein Targeting To Vacuole Golgi To Endosome Transport Mitochondrion Organization Response To Insulin Protein Retention In Golgi Apparatus Negative Regulation Of Parkin-mediated Stimulation Of Mitophagy In Response To Mitochondrial Depolarization
Pathways		TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs		Phosphoaminophosphonic acid guanylate ester Guanosine-5'-Diphosphate
Diseases
GWAS		Refractive error ( 32231278) Serum metabolite levels ( 23093944) Social communication problems ( 24564958)	Asthma ( 29273806) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Body mass index ( 28892062) Breast size ( 27182965) Fasting blood glucose ( 22581228) Fasting blood glucose (BMI interaction) ( 22581228) Fasting blood proinsulin levels ( 23263489) Glaucoma (primary open-angle) ( 29891935) HDL cholesterol levels ( 32203549) Insular cortex volume ( 31530798) Intraocular pressure ( 29785010 31959993 30054594) Parkinson's disease ( 25064009 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Proinsulin levels ( 21873549) Schizophrenia ( 28991256 29483656) Triglyceride levels ( 32203549) Two-hour glucose challenge ( 20081857)
Interacting Genes		7 interacting genes: APP CDH1 RAB3IP RALA TUBA4A TUBB VIM
Entrez ID		51762	54832
HPRD ID		11476	12323
Ensembl ID		ENSG00000166128	ENSG00000129003
Uniprot IDs		Q92930	Q709C8
PDB IDs
Enriched GO Terms of Interacting Partners?
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