ZMYND10 and ACTR3

Data Source:
BioGRID (affinity chromatography technology, pull down)

		ZMYND10	ACTR3
Description		zinc finger MYND-type containing 10	actin related protein 3
Image
GO Annotations	Cellular Component	Cytoplasm Apical Plasma Membrane Centriolar Satellite	Nucleus Cytoplasm Cytosol Arp2/3 Protein Complex Brush Border Cell-cell Junction Focal Adhesion Actin Cytoskeleton Membrane Lamellipodium Site Of Double-strand Break Extracellular Exosome
	Molecular Function	Protein Binding Protein Folding Chaperone Metal Ion Binding Molecular Adaptor Activity	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Actin Filament Binding
	Biological Process	Cilium Movement Protein Folding Outer Dynein Arm Assembly Inner Dynein Arm Assembly Motile Cilium Assembly Protein Localization To Cilium Positive Regulation Of Motile Cilium Assembly	Establishment Or Maintenance Of Cell Polarity Asymmetric Cell Division Positive Regulation Of Lamellipodium Assembly Meiotic Chromosome Movement Towards Spindle Pole Meiotic Cytokinesis Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Transcription By RNA Polymerase II Ephrin Receptor Signaling Pathway Spindle Localization Cilium Assembly Membrane Organization Actin Polymerization-dependent Cell Motility Cellular Response To Interferon-gamma
Pathways			Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Clathrin-mediated endocytosis FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs			N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Metabolite levels ( 23823483) Systolic blood pressure in sickle cell anemia ( 24058526)
Interacting Genes		18 interacting genes: CDR1 CLK1 CYSRT1 EIF3M IFT43 KRTAP10-3 MTUS2 NR0B2 NUTM1 NUTM2F RBM11 RNF181 SERINC1 SNX11 TBX5 TCF4 TSC22D4 WBP1	18 interacting genes: ACTR2 ARPC2 ARPC3 ARPC4 ARPC5 CDC42 CDH1 CTTN ERCC6 HCLS1 JUND LINC01554 SHARPIN UBE3A WASF1 WASF2 WASF3 WASL
Entrez ID		51364	10096
HPRD ID		06145	05024
Ensembl ID		ENSG00000004838	ENSG00000115091
Uniprot IDs		O75800	A0A024RAI1 B4DXW1 P61158
PDB IDs		2D8Q 2DAN	6UHC 6YW6 6YW7
Enriched GO Terms of Interacting Partners?
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