NIN and L2HGDH

Data Source:
BioGRID (biochemical)

		NIN	L2HGDH
Description		ninein	L-2-hydroxyglutarate dehydrogenase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Pericentriolar Material Spindle Pole Nucleoplasm Nucleolus Centrosome Centriole Cytoplasmic Microtubule Plasma Membrane Dendrite Axonal Growth Cone Apical Part Of Cell Mitotic Spindle Mitotic Spindle Pole Ciliary Transition Fiber Centriolar Subdistal Appendage	Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane Integral Component Of Mitochondrial Inner Membrane
	Molecular Function	Calcium Ion Binding Protein Binding GTP Binding Kinase Binding Microtubule Minus-end Binding	(S)-2-hydroxy-acid Oxidase Activity 2-hydroxyglutarate Dehydrogenase Activity
	Biological Process	Protein Localization Centriole-centriole Cohesion Corpus Callosum Morphogenesis Corticospinal Tract Morphogenesis Positive Regulation Of Microtubule Polymerization Microtubule Anchoring At Centrosome Collateral Sprouting Positive Regulation Of Axonogenesis Centrosome Localization Centrosome-templated Microtubule Nucleation	2-oxoglutarate Metabolic Process Cellular Protein Metabolic Process
Pathways			Interconversion of 2-oxoglutarate and 2-hydroxyglutarate
Drugs
Diseases
GWAS		Asthma (time to childhood onset) x early life tobacco smoke interaction ( 31379025) Cognitive performance ( 20125193) Diastolic blood pressure ( 30578418) Lupus nephritis in systemic lupus erythematosus ( 24925725) Mean platelet volume ( 27863252) Periodontal disease-related phenotype (Socransky) ( 24347629) Pulse pressure ( 30578418) Refractive error ( 32231278) Systolic blood pressure ( 30578418)	Estimated glomerular filtration rate ( 31152163 31015462 31451708) Periodontal disease-related phenotype (Socransky) ( 24347629) Systolic blood pressure ( 30224653)
Interacting Genes		14 interacting genes: ABI1 AUNIP AURKA BICD1 GSK3B GTSE1 KLC1 PIAS1 PRKACA RBM10 RTRAF SUMO1 UBE2I YWHAE
Entrez ID		51199	79944
HPRD ID		09785	12640
Ensembl ID		ENSG00000100503	ENSG00000087299
Uniprot IDs		Q5XUU0 Q8N4C6	Q9H9P8
PDB IDs
Enriched GO Terms of Interacting Partners?
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