SAR1B and JADE2

Data Source:
BioGRID (biochemical)

		SAR1B	JADE2
Description		secretion associated Ras related GTPase 1B	jade family PHD finger 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat Golgi Cisterna Membrane Endoplasmic Reticulum Exit Site	Histone Acetyltransferase Complex Nucleoplasm Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding Metal Ion Binding	Protein Binding Transferase Activity Metal Ion Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Regulation Of COPII Vesicle Coating Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Organization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II COPII Vesicle Coating Membrane Organization Positive Regulation Of Protein Exit From Endoplasmic Reticulum	Protein Ubiquitination Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Chylomicron assembly Antigen Presentation: Folding, assembly and peptide loading of class I MHC	HATs acetylate histones
Drugs		Guanosine-5'-Diphosphate
Diseases		Chylomicron retention disease (CRD); Anderson disease
GWAS		Bipolar disorder ( 31043756)	Adult body size ( 32376654) Age at first birth ( 27798627) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Coffee consumption ( 31046077) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hand grip strength ( 29691431) Household income (MTAG) ( 31844048) Mental health study participation (completed survey) ( 31263887) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Platelet distribution width ( 27863252) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 28869590) White blood cell count ( 32888494)
Interacting Genes		3 interacting genes: CIDEB CREB3 TMEM14B	16 interacting genes: CBX8 CDCA7L CSNK2A1 FBXO7 GAS2L2 GORASP2 H3-4 ING4 ING5 MEAF6 PACSIN1 SASH1 ZBTB3 ZBTB5 ZNF417 ZNF496
Entrez ID		51128	23338
HPRD ID		09647	15124
Ensembl ID		ENSG00000152700	ENSG00000043143
Uniprot IDs		Q9Y6B6	A0A0C4DFT8 B3KPL2 B4DFY8 G3XAA4 Q9NQC1
PDB IDs
Enriched GO Terms of Interacting Partners?
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