PCBP1 and MOGS

Data Source:
BioGRID (affinity chromatography technology)

		PCBP1	MOGS
Description		poly(rC) binding protein 1	mannosyl-oligosaccharide glucosidase
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Speck Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding Cadherin Binding Sequence-specific Single Stranded DNA Binding	Mannosyl-oligosaccharide Glucosidase Activity Glucosidase Activity
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of Gene Expression RNA Metabolic Process Viral RNA Genome Replication Positive Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process	Protein Folding Protein N-linked Glycosylation Oligosaccharide Metabolic Process
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	Defective MOGS causes MOGS-CDG (CDG-2b) N-glycan trimming in the ER and Calnexin/Calreticulin cycle Maturation of spike protein Maturation of spike protein
Drugs
Diseases			Congenital disorders of glycosylation (CDG) type II
GWAS		Acne (severe) ( 24927181) Male-pattern baldness ( 28196072)
Interacting Genes		49 interacting genes: ANP32A APP CAV3 CELF2 CELF3 DARS1-AS1 ERG EWSR1 FTH1 GNB2 HMGA1 HNRNPD HNRNPK HNRNPLL HYPK IGF2BP3 KLF1 LMNA MATR3 NOVA1 PABPC1 PCBP2 PCBP4 PDLIM7 PPIG PPIL3 PRPF3 PTBP1 PUF60 QKI RALY RBFOX2 RBM10 RBM11 RBM14 RBM3 RBM42 RBPMS2 SNCG SNRPA SRPK2 SRSF3 TCERG1 TLE5 TSC22D4 UGP2 ZCCHC10 ZNF384 ZNF830	1 interacting genes: CHGB
Entrez ID		5093	7841
HPRD ID		03128	03214
Ensembl ID		ENSG00000169564	ENSG00000115275
Uniprot IDs		Q15365 Q53SS8	A0A384MDR6 Q13724 Q58F09
PDB IDs		1WVN 1ZTG 3VKE
Enriched GO Terms of Interacting Partners?
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