PAM and TBCA

Data Source:
BioGRID (affinity chromatography technology)

		PAM	TBCA
Description		peptidylglycine alpha-amidating monooxygenase	tubulin folding cofactor A
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Trans-Golgi Network Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Transport Vesicle Membrane Secretory Granule Membrane Neuron Projection Perikaryon Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleolus Cytoplasm Cytosol Microtubule Microtubule Cytoskeleton
	Molecular Function	Peptidylglycine Monooxygenase Activity Peptidylamidoglycolate Lyase Activity Copper Ion Binding Calcium Ion Binding Protein Binding Zinc Ion Binding Protein Kinase Binding L-ascorbic Acid Binding Identical Protein Binding	RNA Binding Protein Binding Tubulin Binding Beta-tubulin Binding Chaperone Binding
	Biological Process	Peptide Amidation Response To Hypoxia Long-chain Fatty Acid Metabolic Process Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Heart Development Lactation Response To PH Toxin Metabolic Process Response To Zinc Ion Protein Amidation Protein Phosphopantetheinylation Ovulation Cycle Process Response To Estradiol Regulation Of Actin Cytoskeleton Organization Odontogenesis Response To Drug Response To Copper Ion Regulation Of Protein Secretion Response To Glucocorticoid Maternal Process Involved In Female Pregnancy Limb Development Fatty Acid Primary Amide Biosynthetic Process	Protein Folding Tubulin Complex Assembly Post-chaperonin Tubulin Folding Pathway
Pathways			Post-chaperonin tubulin folding pathway
Drugs		Ascorbic acid N-Alpha-Acetyl-3,5-Diiodotyrosylglycine N-alpha-Acetyl-3,5-diiodotyrosyl-D-threonine
Diseases
GWAS		Appendicular lean mass ( 33097823) Blood protein levels ( 30072576 29875488) Diastolic blood pressure ( 29208002) Early cardiac repolarization ( 31600170) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Feeling worry ( 29500382) Insulinogenic index ( 23263489) Medication use (drugs used in diabetes) ( 31015401) Nicotine dependence symptom count ( 25555482) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) PR interval ( 30046033 32439900) Primary biliary cholangitis ( 26394269) Refractive error ( 32231278) Sleep duration (short sleep) ( 30846698) Systolic blood pressure ( 29208002) Type 2 diabetes ( 30054458 29358691 30297969 29632382) Type 2 diabetes (adjusted for BMI) ( 29632382)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494) Platelet distribution width ( 32888494)
Interacting Genes		9 interacting genes: CALM1 FXYD1 GLP1R KALRN POMC PRKCA RASSF9 TSC2 UHMK1	4 interacting genes: CDC42 ERBB3 TAF9 TERF2IP
Entrez ID		5066	6902
HPRD ID		01361	18166
Ensembl ID		ENSG00000145730	ENSG00000171530
Uniprot IDs		O43832 P19021	E5RIX8 O75347 Q6FGD7
PDB IDs			1H7C
Enriched GO Terms of Interacting Partners?
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