SLC45A1 and SDHB

Data Source:
HPRD (in vivo)

		SLC45A1	SDHB
Description		solute carrier family 45 member 1	succinate dehydrogenase complex iron sulfur subunit B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane Integral Component Of Membrane	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex II, Succinate Dehydrogenase Complex (ubiquinone) Plasma Membrane Mitochondrial Membrane
	Molecular Function	Sucrose:proton Symporter Activity	Protein Binding Succinate Dehydrogenase (ubiquinone) Activity Electron Transfer Activity Metal Ion Binding Ubiquinone Binding 2 Iron, 2 Sulfur Cluster Binding 3 Iron, 4 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Sucrose Transport Glucose Transmembrane Transport	Tricarboxylic Acid Cycle Succinate Metabolic Process Aerobic Respiration Respiratory Electron Transport Chain
Pathways			Respiratory electron transport Citric acid cycle (TCA cycle)
Drugs			2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol Ubiquinone Q1
Diseases
GWAS		Allergic rhinitis ( 30013184) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Blond vs. brown/black hair color ( 30531825) Breast cancer ( 23468962) Brown vs. black hair color ( 30531825) Depression ( 29700475) Fish- and plant-related diet ( 32066663) Hair color ( 29662168) Hair shape ( 29220522) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hippocampal volume in normal cognition ( 29274321) Inflammatory skin disease ( 25574825) Morning person ( 30696823) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Psoriasis ( 25903422 23143594) Schizophrenia ( 28991256 29483656) Strep throat ( 28928442) Subclinical trait of interstitial lung disease (basilar peel-core ratio of high attentuation areas on CT scan) ( 28521775) Youthful appearance (self-reported) ( 32339537)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Height ( 20189936) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		1 interacting genes: PPP1CA	6 interacting genes: ABCA1 CARTPT GEM PIK3R5 SPRY2 XRN1
Entrez ID		50651	6390
HPRD ID		19078	01707
Ensembl ID		ENSG00000162426	ENSG00000117118
Uniprot IDs		Q9Y2W3	P21912
PDB IDs
Enriched GO Terms of Interacting Partners?
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