PCSK6 and FN3K

Data Source:
BioGRID (affinity chromatography technology)

		PCSK6	FN3K
Description		proprotein convertase subtilisin/kexin type 6	fructosamine 3 kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Golgi Lumen Plasma Membrane Cell Surface Membrane Collagen-containing Extracellular Matrix	Cellular_component Cytosol
	Molecular Function	Endopeptidase Activity Serine-type Endopeptidase Activity Protein Binding Heparin Binding Nerve Growth Factor Binding	ATP Binding Kinase Activity Fructosamine-3-kinase Activity Protein-ribulosamine 3-kinase Activity Protein-fructosamine 3-kinase Activity
	Biological Process	Glycoprotein Metabolic Process Protein Processing Peptide Hormone Processing Regulation Of BMP Signaling Pathway Nerve Growth Factor Processing Nerve Growth Factor Production Secretion By Cell Regulation Of Lipoprotein Lipase Activity Cornification	Phosphorylation Protein Phosphopantetheinylation Fructosamine Metabolic Process Fructoselysine Metabolic Process Epithelial Cell Differentiation Protein Deglycation Post-translational Protein Modification
Pathways		Signaling by NODAL NGF processing Formation of the cornified envelope Assembly of active LPL and LIPC lipase complexes	Gamma carboxylation, hypusine formation and arylsulfatase activation
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Cytokine levels ( 31679650) Cytokine network levels (multivariate analysis) ( 31679650) Handedness in dyslexia ( 21051773) Height ( 31562340) Inflammatory biomarkers (multivariate analysis) ( 33110245) Platelet-derived growth factor BB levels ( 27989323) Red blood cell count ( 32888494) Relative hand skill in reading disability ( 24068947) Triglyceride levels ( 32203549) Triglycerides ( 30275531) Tuberculosis ( 30713548) Type 2 diabetes ( 30470734)	Glycated hemoglobin levels ( 24647736 20858683 24244560 31213470 29170429) Hemoglobin A1c levels ( 29403010 31217584) Platelet distribution width ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		6 interacting genes: CACNA1A FLG PCSK5 PMCH RCN3 ZNF441
Entrez ID		5046	64122
HPRD ID		01329	16336
Ensembl ID		ENSG00000140479	ENSG00000167363
Uniprot IDs		A2RQD9 H7BXT3 P29122 Q59H04	Q9H479
PDB IDs
Enriched GO Terms of Interacting Partners?
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