NUCB2 and NFRKB

Data Source:
BioGRID (enzymatic study)

		NUCB2	NFRKB
Description		nucleobindin 2	nuclear factor related to kappaB binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Plasma Membrane Extracellular Exosome	Nucleus Nucleoplasm Ino80 Complex
	Molecular Function	G-protein Alpha-subunit Binding DNA Binding Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding	Protease Binding DNA Binding Protein Binding
	Biological Process	Small GTPase Mediated Signal Transduction Negative Regulation Of Appetite Regulation Of Catalytic Activity	DNA Repair DNA Recombination Protein Deubiquitination
Pathways			UCH proteinases DNA Damage Recognition in GG-NER
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Blood protein levels ( 29875488) Body mass index ( 26426971) Height ( 20881960) Mean platelet volume ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878 28739976) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28448500) Youthful appearance (self-reported) ( 32339537)	High light scatter reticulocyte count ( 32888494) Night sleep phenotypes ( 27126917) Reticulocyte count ( 32888494)
Interacting Genes		12 interacting genes: ARL13B ASPH FFAR2 GADD45A GNAI3 GNAS NDN NR1I2 SLC7A1 SMARCD1 STAR XPO1	4 interacting genes: EPHB3 NFKB1 TRDMT1 UCHL5
Entrez ID		4925	4798
HPRD ID		09726	01240
Ensembl ID		ENSG00000070081	ENSG00000170322
Uniprot IDs		P80303 Q2L696	A0A024R3K9 Q6P4R8
PDB IDs			3U21 4UF5 4UF6 4WLP
Enriched GO Terms of Interacting Partners?
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