MX2 and STK38L

Data Source:
BioGRID (proximity labelling technology)

		MX2	STK38L
Description		MX dynamin like GTPase 2	serine/threonine kinase 38 like
Image
GO Annotations	Cellular Component	Nucleus Nuclear Pore Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Microtubule Cytoskeleton Membrane Axon Cytoplasmic Vesicle Mitochondrial Membrane Dendritic Spine Head Presynapse Postsynaptic Endocytic Zone Membrane	Cytoplasm Cytosol Actin Cytoskeleton Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Microtubule Binding	Magnesium Ion Binding Actin Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Mitochondrial Fission Dynamin Family Protein Polymerization Involved In Mitochondrial Fission Defense Response Response To Virus Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Receptor Internalization Response To Interferon-alpha Regulation Of Nucleocytoplasmic Transport Regulation Of Synapse Structure Or Activity MRNA Transport Defense Response To Virus Regulation Of Cell Cycle Type I Interferon Signaling Pathway Membrane Fusion Postsynaptic Neurotransmitter Receptor Internalization	Protein Phosphorylation Peptidyl-serine Phosphorylation Intracellular Signal Transduction Regulation Of Cellular Component Organization
Pathways		ISG15 antiviral mechanism Interferon alpha/beta signaling
Drugs			Fostamatinib
Diseases
GWAS		Cutaneous malignant melanoma ( 32341527) Melanoma ( 21983787 28212542) Nevus count or cutaneous melanoma ( 32341527 30429480) Parkinson disease and lewy body pathology ( 25663231)	Diastolic blood pressure ( 30224653) Glioma ( 30714141) Mean platelet volume ( 32888494)
Interacting Genes		3 interacting genes: ATRIP EHMT2 PIAS2	3 interacting genes: MOB2 STK24 YWHAB
Entrez ID		4600	23012
HPRD ID		01001	10256
Ensembl ID		ENSG00000183486	ENSG00000211455
Uniprot IDs		P20592	Q9Y2H1
PDB IDs		4WHJ 4X0R 5UOT	5XQZ
Enriched GO Terms of Interacting Partners?
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