IDH3B and TNFRSF9

Data Source:
BioGRID (two hybrid)

		IDH3B	TNFRSF9
Description		isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta	TNF receptor superfamily member 9
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GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Magnesium Ion Binding Isocitrate Dehydrogenase (NAD+) Activity Electron Transfer Activity NAD Binding	Protein Binding Cytokine Binding Signaling Receptor Activity
	Biological Process	Tricarboxylic Acid Cycle Isocitrate Metabolic Process Electron Transport Chain	Apoptotic Process Negative Regulation Of Cell Population Proliferation Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Cell Population Proliferation
Pathways		Citric acid cycle (TCA cycle)	TNFs bind their physiological receptors
Drugs		NADH	Urelumab
Diseases		Retinitis pigmentosa (RP)
GWAS			Blond vs. brown/black hair color ( 30531825) Celiac disease ( 20190752) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Psoriasis ( 25903422 23143594) Rheumatoid arthritis ( 30423114 24390342) Ulcerative colitis ( 28067908 21297633) Waist-hip ratio ( 28552196)
Interacting Genes		6 interacting genes: ATXN2 IDH3A IDH3G MAPK6 PRMT1 RAB35	7 interacting genes: LRR1 SERP1 TNFRSF4 TNFSF9 TRAF1 TRAF2 TRAF3
Entrez ID		3420	3604
HPRD ID		05163	03767
Ensembl ID		ENSG00000101365	ENSG00000049249
Uniprot IDs		A0A087WZN1 A0A087X2E5 O43837	Q07011
PDB IDs		6KDE 6KDF 6KDY 6KE3	6A3V 6A3W 6BWV 6CPR 6CU0 6MGP 6MHR 6MI2
Enriched GO Terms of Interacting Partners?
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