ACADM and ABCD3

Data Source:
BioGRID (affinity chromatography technology)

		ACADM	ABCD3
Description		acyl-CoA dehydrogenase medium chain	ATP binding cassette subfamily D member 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Axon Mitochondrial Membrane	Mitochondrion Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Acyl-CoA Dehydrogenase Activity Identical Protein Binding Flavin Adenine Dinucleotide Binding Medium-chain-acyl-CoA Dehydrogenase Activity	Long-chain Fatty Acid Transporter Activity Protein Binding ATP Binding ATPase Activity ATPase-coupled Transmembrane Transporter Activity Protein Homodimerization Activity Protein Self-association
	Biological Process	Fatty Acid Beta-oxidation Regulation Of Lipid Metabolic Process Carnitine Metabolic Process, CoA-linked Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase Carnitine Biosynthetic Process Medium-chain Fatty Acid Metabolic Process Medium-chain Fatty Acid Catabolic Process	Fatty Acid Biosynthetic Process Fatty Acid Beta-oxidation Peroxisome Organization Response To Organic Cyclic Compound Long-chain Fatty Acid Import Into Peroxisome Response To Drug Very Long-chain Fatty Acid Catabolic Process Transmembrane Transport
Pathways		PPARA activates gene expression mitochondrial fatty acid beta-oxidation of unsaturated fatty acids Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA Beta oxidation of octanoyl-CoA to hexanoyl-CoA	ABC transporters in lipid homeostasis Class I peroxisomal membrane protein import
Drugs		Octanoyl-Coenzyme A Flavin adenine dinucleotide 3-thiaoctanoyl-CoA
Diseases		Disorders of fatty-acid oxidation, including: Medium-chain (MC) acyl-CoA dehydrogenase (AD) deficiency (MCADD); Short-chain AD deficiency (SCADD) ; Short-branched-chain AD deficiency (SBCADD) ; Very long-chain AD deficiency (VLCADD) ; Long-chain 3-hydroxyacyl CoA dehydrogenase deficiency (LCHADD) ; Trifunctional protein deficiency (TFP); Carnitine palmitoyltransferase deficiency (CPT); Carnitine-acylcarnitine translocase deficiency (CACT); Systemic primary carnitine deficiency (CDSP)
GWAS		Acylcarnitine levels ( 26068415) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Daytime sleep phenotypes ( 27126917) Glycine levels ( 31070104 30837465) Metabolic traits ( 21886157) Metabolite levels ( 20037589) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 23093944) Serum metabolite ratios in chronic kidney disease ( 29545352) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
Interacting Genes		3 interacting genes: CALM1 CDC42 SUMO4	6 interacting genes: ABCD1 ABCD2 COL6A2 PEX19 PSMA1 TUFT1
Entrez ID		34	5825
HPRD ID		08447	01368
Ensembl ID		ENSG00000117054	ENSG00000117528
Uniprot IDs		A0A0S2Z366 B4DJE7 B7Z9I1 P11310 Q5HYG7 Q5T4U5	P28288
PDB IDs		1EGC 1EGD 1EGE 1T9G 2A1T 4P13
Enriched GO Terms of Interacting Partners?
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