FOXN2 and LTBP1

Data Source:
BioGRID (affinity chromatography technology)

		FOXN2	LTBP1
Description		forkhead box N2	latent transforming growth factor beta binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle	Microfibril Extracellular Region Endoplasmic Reticulum Lumen Extracellular Matrix Protein-containing Complex Collagen-containing Extracellular Matrix
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Transforming Growth Factor Beta-activated Receptor Activity Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Transforming Growth Factor Beta Binding Microfibril Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Cell Differentiation	Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Sequestering Of TGFbeta In Extracellular Matrix Post-translational Protein Modification Cellular Protein Metabolic Process Regulation Of Transforming Growth Factor Beta Activation
Pathways			Molecules associated with elastic fibres Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Bitter alcoholic beverage consumption ( 31046077) Chronotype ( 30696823) Glycated hemoglobin levels ( 28898252) HDL cholesterol levels ( 32203549) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Left-handedness ( 32989287) Macular thickness ( 30535121)	Carpal tunnel syndrome ( 30833571) Central corneal thickness ( 32528159 29760442) Diverticular disease ( 30177863) Height ( 28552196 20881960 25282103 25429064 19893584 23563607 31562340 20189936) Hip circumference adjusted for BMI ( 25673412) Immune reponse to smallpox (secreted IFN-alpha) ( 22610502) Immune response to smallpox vaccine (IL-6) ( 22610502) Intraocular pressure ( 29617998 29785010 29235454) Knee osteoarthritis ( 30374069) Male-pattern baldness ( 28196072) Optic disc size ( 31809533) Rosacea symptom severity ( 29771307) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412 28448500)
Interacting Genes		1 interacting genes: USP7	11 interacting genes: ATN1 CACNA1A FBN1 FBN2 FN1 HTRA1 IGFBP3 IGFBP5 ITGB5 TGFB1 TGM2
Entrez ID		3344	4052
HPRD ID		00882	01039
Ensembl ID		ENSG00000170802	ENSG00000049323
Uniprot IDs		P32314	B7ZLY3 Q14766
PDB IDs			1KSQ
Enriched GO Terms of Interacting Partners?
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