HGD and ACSL6

Data Source:
HPRD (in vitro, in vivo)

		HGD	ACSL6
Description		homogentisate 1,2-dioxygenase	acyl-CoA synthetase long chain family member 6
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome	Mitochondrial Outer Membrane Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Homogentisate 1,2-dioxygenase Activity Protein Binding Identical Protein Binding Metal Ion Binding	Long-chain Fatty Acid-CoA Ligase Activity ATP Binding Protein Homodimerization Activity Arachidonate-CoA Ligase Activity
	Biological Process	L-phenylalanine Catabolic Process Tyrosine Catabolic Process	Very Long-chain Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Lipid Biosynthetic Process Long-chain Fatty-acyl-CoA Biosynthetic Process
Pathways		Tyrosine catabolism	Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases		Alkaptonuria
GWAS			Alzheimer's disease in APOE e4- carriers ( 25778476) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908 22412388) Inflammatory bowel disease ( 28067908 23128233) Perceived unattractiveness to mosquitoes ( 28199695) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		5 interacting genes: CLDN7 GIT2 NTAQ1 PCDHGC3 TERF1	3 interacting genes: PCMTD2 PHYH ZNF655
Entrez ID		3081	23305
HPRD ID		06315	09190
Ensembl ID		ENSG00000113924	ENSG00000164398
Uniprot IDs		B3KW64 Q93099	B2RB13 B4DFW3 Q9UKU0
PDB IDs		1EY2 1EYB
Enriched GO Terms of Interacting Partners?
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