ANXA3 and BAG5

Data Source:
BioGRID (affinity chromatography technology)

		ANXA3	BAG5
Description		annexin A3	BAG cochaperone 5
Image
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane Axon Dendrite Phagocytic Vesicle Membrane Specific Granule Neuronal Cell Body Extracellular Exosome	Nucleus Cytoplasm Mitochondrion Cytosol Membrane Inclusion Body Perinuclear Region Of Cytoplasm
	Molecular Function	Calcium Ion Binding Calcium-dependent Phospholipid Binding Phospholipase A2 Inhibitor Activity Calcium-dependent Protein Binding	Adenyl-nucleotide Exchange Factor Activity Protein Binding Protein Kinase Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Chaperone Binding
	Biological Process	Phagocytosis Positive Regulation Of Endothelial Cell Migration Hippocampus Development Animal Organ Regeneration Defense Response To Bacterium Negative Regulation Of Catalytic Activity Neutrophil Degranulation Positive Regulation Of Angiogenesis Positive Regulation Of DNA Metabolic Process Positive Regulation Of DNA-binding Transcription Factor Activity Response To Glucocorticoid Response To Growth Factor	Protein Folding Golgi Organization Negative Regulation Of Neuron Projection Development Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Protein Refolding Neuron Death Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways			Regulation of HSF1-mediated heat shock response
Drugs		Fluocinolone acetonide Ethanolamine Difluocortolone
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Metabolite levels ( 23823483) Non-albumin protein levels ( 22558069) Refractive error ( 32231278) Rheumatoid arthritis ( 30423114 22446963)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Broad depression or schizophrenia ( 30626913) Depression ( 29700475) Schizophrenia ( 25056061)
Interacting Genes		6 interacting genes: EMG1 IGSF21 REG3A TP53 UBR1 UNC119	19 interacting genes: BANP CDCA7L CIRBP DES EFEMP1 FAM118B GOLGA6A HSPA4 KASH5 KRTAP5-4 LRRK1 MAD1L1 PINK1 PRKN SNCA STUB1 THAP1 TP53 TRIM27
Entrez ID		306	9529
HPRD ID		00111	04862
Ensembl ID		ENSG00000138772	ENSG00000166170
Uniprot IDs		P12429	A0A024R6M6 Q9UL15
PDB IDs		1AII 1AXN	2D9D 3A8Y
Enriched GO Terms of Interacting Partners?
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