XCR1 and TOPAZ1

Data Source:
BioGRID (biochemical)

		XCR1	TOPAZ1
Description		X-C motif chemokine receptor 1	testis and ovary specific PAZ domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Cytosol
	Molecular Function	Chemokine Receptor Activity Protein Binding C-C Chemokine Receptor Activity C-C Chemokine Binding
	Biological Process	Chemotaxis Inflammatory Response Immune Response G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Release Of Sequestered Calcium Ion Into Cytosol Cell Chemotaxis Chemokine-mediated Signaling Pathway	Apoptotic Process Spermatid Development Spermatocyte Division NcRNA Transcription Positive Regulation Of Meiotic Cell Cycle Phase Transition
Pathways		Chemokine receptors bind chemokines G alpha (q) signalling events
Drugs
Diseases
GWAS		Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485)	Adult body size ( 32376654) Adventurousness ( 30643258) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) General risk tolerance (MTAG) ( 30643258)
Interacting Genes		3 interacting genes: PLEKHF2 XCL1 XCL2
Entrez ID		2829	375337
HPRD ID		02774	19563
Ensembl ID		ENSG00000173578	ENSG00000173769
Uniprot IDs		P46094 Q502V0 Q689E2	Q8N9V7
PDB IDs
Enriched GO Terms of Interacting Partners?
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