NECTIN3 and IQCB1

Data Source:
BioGRID (biochemical)

		NECTIN3	IQCB1
Description		nectin cell adhesion molecule 3	IQ motif containing B1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Adherens Junction Axon Dendrite Apical Junction Complex Cell-cell Contact Zone Hippocampal Mossy Fiber To CA3 Synapse Integral Component Of Postsynaptic Density Membrane	Photoreceptor Outer Segment Nucleoplasm Centrosome Centriole Cytosol Cilium Microtubule Cytoskeleton Photoreceptor Connecting Cilium Intercellular Bridge Extracellular Exosome Mitotic Spindle
	Molecular Function	Protein Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding	Protein Binding Calmodulin Binding Enzyme Binding
	Biological Process	Lens Morphogenesis In Camera-type Eye Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Spermatid Development Fertilization Adherens Junction Organization Retina Morphogenesis In Camera-type Eye Establishment Of Protein Localization To Plasma Membrane Protein Localization To Cell Junction	Photoreceptor Cell Maintenance Maintenance Of Animal Organ Identity Cilium Assembly Ciliary Basal Body-plasma Membrane Docking
Pathways		Adherens junctions interactions Nectin/Necl trans heterodimerization	Anchoring of the basal body to the plasma membrane
Drugs
Diseases			Senior-Loken syndrome
GWAS		Feeling hurt ( 29500382)	Hemoglobin levels ( 32327693) Multiple sclerosis ( 31604244 24076602) Multiple sclerosis and triglyceride levels (pleiotropy) ( 26920376)
Interacting Genes		22 interacting genes: AFDN CYSRT1 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-1 KRTAP4-2 KRTAP5-11 KRTAP5-9 KRTAP9-3 NBPF19 NECTIN1 NECTIN2 NOTCH2NLA OTX1 PARD3 PVR RGS20 TIGIT	12 interacting genes: CALM2 CALML3 KIF9 LDOC1 MARCHF7 MNS1 PCMT1 PDE9A SESTD1 SMARCD1 SPG21 TRIM32
Entrez ID		25945	9657
HPRD ID		08454	11049
Ensembl ID		ENSG00000177707	ENSG00000173226
Uniprot IDs		Q9NQS3	Q15051
PDB IDs		4FOM
Enriched GO Terms of Interacting Partners?
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