DNAJB5 and SIGMAR1

Data Source:
BioGRID (biochemical)

		DNAJB5	SIGMAR1
Description		DnaJ heat shock protein family (Hsp40) member B5	sigma non-opioid intracellular receptor 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Postsynaptic Density Membrane Integral Component Of Membrane Growth Cone Cytoplasmic Vesicle Postsynaptic Density Membrane
	Molecular Function	Protein Binding Unfolded Protein Binding Chaperone Binding	Opioid Receptor Activity Protein Binding
	Biological Process	Response To Unfolded Protein Chaperone Cofactor-dependent Protein Refolding	Lipid Transport Nervous System Development Cell Death In Response To Hydrogen Peroxide Opioid Receptor Signaling Pathway Regulation Of Neuron Apoptotic Process Protein Homotrimerization
Pathways			Potential therapeutics for SARS
Drugs			Amitriptyline Remoxipride Haloperidol Dextromethorphan Nortriptyline Fenfluramine Pentazocine Cocaine Hydrocodone Sertraline Dimethyltryptamine Prasterone Phencyclidine Noscapine Captodiame Pentoxyverine
Diseases
GWAS		Response to quetiapine in schizophrenia ( 29503163)
Interacting Genes		11 interacting genes: ANK2 CACNA1A MRFAP1 MYBPC1 NOCT OBSCN SMAD2 SMAD3 TAF1 TBPL2 TTN	3 interacting genes: ANK2 ITPR3 PDZD11
Entrez ID		25822	10280
HPRD ID		07106	03580
Ensembl ID		ENSG00000137094	ENSG00000147955
Uniprot IDs		O75953	A2A3U5 B4DR71 Q99720
PDB IDs			5HK1 5HK2 6DJZ 6DK0 6DK1
Enriched GO Terms of Interacting Partners?
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