CLDN14 and POFUT2

Data Source:
BioGRID (affinity chromatography technology)

		CLDN14	POFUT2
Description		claudin 14	protein O-fucosyltransferase 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane	Endoplasmic Reticulum Membrane Golgi Apparatus
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding	Peptide-O-fucosyltransferase Activity
	Biological Process	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Protein-containing Complex Assembly Bicellular Tight Junction Assembly	Mesoderm Formation Fucose Metabolic Process Regulation Of Gene Expression Regulation Of Epithelial To Mesenchymal Transition Protein O-linked Fucosylation Regulation Of Secretion Positive Regulation Of Protein Folding
Pathways		Tight junction interactions	O-glycosylation of TSR domain-containing proteins
Drugs
Diseases		Deafness, autosomal recessive
GWAS		Blood urea nitrogen levels ( 31152163) Bone mineral density ( 24249740) Estimated glomerular filtration rate ( 31152163 31015462) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 30598549) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Kidney stones ( 26272126 19561606 31729369) Red blood cell count ( 32888494) Serum parathyroid hormone levels ( 27927781) Urate levels ( 31578528) Urinary electrolytes (magnesium/calcium ratio) ( 27915449) Urolithiasis ( 30975718)	Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Logical memory (immediate recall) in mild cognitive impairment ( 29274321)
Interacting Genes		4 interacting genes: CTXN3 MAL PLEKHA1 PLLP
Entrez ID		23562	23275
HPRD ID		05727	09846
Ensembl ID		ENSG00000159261	ENSG00000186866
Uniprot IDs		O95500	Q9Y2G5 S6FW71
PDB IDs			4AP5 4AP6
Enriched GO Terms of Interacting Partners?
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