TSPAN15 and TCHP

Data Source:
BioGRID (affinity chromatography technology)

		TSPAN15	TCHP
Description		tetraspanin 15	trichoplein keratin filament binding
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Cytosol Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Nuclear Body Cell Junction Late Endosome Membrane Intracellular Membrane-bounded Organelle Tetraspanin-enriched Microdomain	Cytoplasm Mitochondrion Centrosome Cytosol Plasma Membrane Desmosome Keratin Filament Apical Cortex
	Molecular Function	Protein Binding Enzyme Binding	Protein Binding
	Biological Process	Regulation Of Notch Signaling Pathway Cellular Protein Metabolic Process Negative Regulation Of Notch Signaling Pathway Protein Maturation Protein Localization To Plasma Membrane	Apoptotic Process Cell Projection Organization Negative Regulation Of Cell Growth Negative Regulation Of Cilium Assembly
Pathways		Amyloid fiber formation
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Height ( 31562340) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Response to taxane treatment (placlitaxel) ( 23006423) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Thrombosis ( 26908601) Type 2 diabetes ( 32499647) Venous thromboembolism ( 25772935 28373160 31420334 31676865)	Bipolar disorder ( 31043756) Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia ( 28922980) Metabolite levels (MHPG) ( 23319000) Myocardial infarction ( 30226566) Platelet count ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		5 interacting genes: BTRC GYPC RGS2 STRIT1 SYNE4	52 interacting genes: ATPAF2 BCAS2 C21orf91 CBY2 CCDC125 CCDC13 CCDC172 CCDC85B CDR2 CDR2L DMAP1 DYDC1 EIF4ENIF1 HOOK2 ID2 IFFO1 IKZF3 KCTD17 KIAA0753 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT32 KRT34 KRT35 KRT40 KRT5 KRT6A KRT75 KRT8 MIIP MIPOL1 MKRN3 MTUS2 NAB2 NDOR1 NME7 NUP54 PRDM16 PSMB5 RABGEF1 RUSC1 TEX11 TRIM27 TRIM54 USHBP1 VIM WWOX ZIM2
Entrez ID		23555	84260
HPRD ID		15511	14403
Ensembl ID		ENSG00000099282	ENSG00000139437
Uniprot IDs		O95858	A0A024RBM9 Q9BT92
PDB IDs
Enriched GO Terms of Interacting Partners?
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