TSPAN15 and CHI3L1

Data Source:
BioGRID (genetic interference, affinity chromatography technology)

		TSPAN15	CHI3L1
Description		tetraspanin 15	chitinase 3 like 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Cytosol Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Nuclear Body Cell Junction Late Endosome Membrane Intracellular Membrane-bounded Organelle Tetraspanin-enriched Microdomain	Extracellular Region Extracellular Space Cytoplasm Endoplasmic Reticulum Extracellular Matrix Specific Granule Lumen Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding Enzyme Binding	Chitinase Activity Extracellular Matrix Structural Constituent Protein Binding Chitin Binding Carbohydrate Binding
	Biological Process	Regulation Of Notch Signaling Pathway Cellular Protein Metabolic Process Negative Regulation Of Notch Signaling Pathway Protein Maturation Protein Localization To Plasma Membrane	Carbohydrate Metabolic Process Chitin Catabolic Process Apoptotic Process Inflammatory Response Activation Of NF-kappaB-inducing Kinase Activity Response To Mechanical Stimulus Positive Regulation Of Peptidyl-threonine Phosphorylation Lung Development Interleukin-8 Production Response To Tumor Necrosis Factor Neutrophil Degranulation Positive Regulation Of Angiogenesis Cartilage Development Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of ERK1 And ERK2 Cascade Response To Interleukin-1 Response To Interleukin-6 Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor
Pathways		Amyloid fiber formation	Neutrophil degranulation
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Height ( 31562340) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Response to taxane treatment (placlitaxel) ( 23006423) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Thrombosis ( 26908601) Type 2 diabetes ( 32499647) Venous thromboembolism ( 25772935 28373160 31420334 31676865)	Asthma ( 31959851) Blood protein levels ( 29875488) Blood protein levels in cardiovascular risk ( 28369058) Clozapine-induced agranulocytosis ( 25187353) Metabolite levels ( 23823483) YKL-40 levels ( 18403759)
Interacting Genes		5 interacting genes: BTRC GYPC RGS2 STRIT1 SYNE4
Entrez ID		23555	1116
HPRD ID		15511	03314
Ensembl ID		ENSG00000099282	ENSG00000133048
Uniprot IDs		O95858	A0A024R969 P36222
PDB IDs			1HJV 1HJW 1HJX 1LA7 1NWR 1NWS 1NWT 1NWU
Enriched GO Terms of Interacting Partners?
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