SYNE1 and ZC3H12D

Data Source:
BioGRID (affinity chromatography technology)

		SYNE1	ZC3H12D
Description		spectrin repeat containing nuclear envelope protein 1	zinc finger CCCH-type containing 12D
Image			No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Nuclear Envelope Nuclear Outer Membrane Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytoskeleton Integral Component Of Membrane Sarcomere Nuclear Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex Postsynaptic Membrane	P-body Nucleus Nucleoplasm Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	RNA Binding Actin Binding Protein Binding Lamin Binding Enzyme Binding Protein Homodimerization Activity Actin Filament Binding Cytoskeleton-nuclear Membrane Anchor Activity	MRNA Binding Endoribonuclease Activity Protein Binding Metal Ion Binding
	Biological Process	Nucleus Organization Golgi Organization Spermatogenesis Muscle Cell Differentiation Nuclear Matrix Anchoring At Nuclear Membrane	MRNA Catabolic Process 3'-UTR-mediated MRNA Destabilization RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		Meiotic synapsis
Drugs
Diseases		Emery-Dreifuss muscular dystrophy Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Bipolar disorder ( 28115744 21926972 31043756 28072414 20351715 21738484) Bipolar disorder or major depressive disorder ( 20351715) Bipolar I disorder ( 31043756) Body mass index ( 26426971) Endometriosis ( 28537267) Heel bone mineral density ( 30598549 28869591) Post bronchodilator FEV1 ( 26634245) Tonometry ( 17903302) Uterine fibroids ( 31249589 30194396 31649266)	Asthma ( 32296059) Dupuytren's disease ( 28886342 21732829) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494)
Interacting Genes		21 interacting genes: ACTC1 APC BDKRB2 CAPN1 CDC42 CDC5L CEP63 DISC1 DTNBP1 ECPAS EMD LINC00839 LMNA MTDH MUSK MYOM1 NDEL1 SH3BP5 TNIK TP53RK USP21	1 interacting genes: ZC3H12A
Entrez ID		23345	340152
HPRD ID		09762	19272
Ensembl ID		ENSG00000131018	ENSG00000178199
Uniprot IDs		A0A0C4DG40 B4E3R1 B7Z9Y6 F8WAI0 Q8NF91	A2A288
PDB IDs		4DXR 6R15
Enriched GO Terms of Interacting Partners?
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