JADE2 and DDX46

Data Source:
BioGRID (proximity labelling technology)

		JADE2	DDX46
Description		jade family PHD finger 2	DEAD-box helicase 46
Image		No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleoplasm Extracellular Exosome	Fibrillar Center Nucleus Nucleoplasm Cajal Body Membrane Nuclear Speck
	Molecular Function	Protein Binding Transferase Activity Metal Ion Binding	RNA Binding RNA Helicase Activity ATP Binding
	Biological Process	Protein Ubiquitination Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation	MRNA Splicing, Via Spliceosome
Pathways		HATs acetylate histones	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first birth ( 27798627) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Coffee consumption ( 31046077) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hand grip strength ( 29691431) Household income (MTAG) ( 31844048) Mental health study participation (completed survey) ( 31263887) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Platelet distribution width ( 27863252) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 28869590) White blood cell count ( 32888494)	Height ( 18391951)
Interacting Genes		16 interacting genes: CBX8 CDCA7L CSNK2A1 FBXO7 GAS2L2 GORASP2 H3-4 ING4 ING5 MEAF6 PACSIN1 SASH1 ZBTB3 ZBTB5 ZNF417 ZNF496	3 interacting genes: APBB1 LINC01554 SRPK2
Entrez ID		23338	9879
HPRD ID		15124	10862
Ensembl ID		ENSG00000043143	ENSG00000145833
Uniprot IDs		A0A0C4DFT8 B3KPL2 B4DFY8 G3XAA4 Q9NQC1	A0A0C4DG89 Q7L014
PDB IDs			6Y50 6Y53 6Y5Q
Enriched GO Terms of Interacting Partners?
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