JADE2 and SAR1B

Data Source:
BioGRID (biochemical)

		JADE2	SAR1B
Description		jade family PHD finger 2	secretion associated Ras related GTPase 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleoplasm Extracellular Exosome	Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat Golgi Cisterna Membrane Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding Transferase Activity Metal Ion Binding	GTPase Activity Protein Binding GTP Binding Metal Ion Binding
	Biological Process	Protein Ubiquitination Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Regulation Of COPII Vesicle Coating Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Organization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II COPII Vesicle Coating Membrane Organization Positive Regulation Of Protein Exit From Endoplasmic Reticulum
Pathways		HATs acetylate histones	Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Chylomicron assembly Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs			Guanosine-5'-Diphosphate
Diseases			Chylomicron retention disease (CRD); Anderson disease
GWAS		Adult body size ( 32376654) Age at first birth ( 27798627) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Coffee consumption ( 31046077) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hand grip strength ( 29691431) Household income (MTAG) ( 31844048) Mental health study participation (completed survey) ( 31263887) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Platelet distribution width ( 27863252) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 28869590) White blood cell count ( 32888494)	Bipolar disorder ( 31043756)
Interacting Genes		16 interacting genes: CBX8 CDCA7L CSNK2A1 FBXO7 GAS2L2 GORASP2 H3-4 ING4 ING5 MEAF6 PACSIN1 SASH1 ZBTB3 ZBTB5 ZNF417 ZNF496	3 interacting genes: CIDEB CREB3 TMEM14B
Entrez ID		23338	51128
HPRD ID		15124	09647
Ensembl ID		ENSG00000043143	ENSG00000152700
Uniprot IDs		A0A0C4DFT8 B3KPL2 B4DFY8 G3XAA4 Q9NQC1	Q9Y6B6
PDB IDs
Enriched GO Terms of Interacting Partners?
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