JADE2 and FSTL4

Data Source:
HPRD (in vitro)

		JADE2	FSTL4
Description		jade family PHD finger 2	follistatin like 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleoplasm Extracellular Exosome	Extracellular Region Secretory Granule
	Molecular Function	Protein Binding Transferase Activity Metal Ion Binding	Calcium Ion Binding Brain-derived Neurotrophic Factor Binding
	Biological Process	Protein Ubiquitination Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation	Multicellular Organism Development Cell Differentiation Negative Regulation Of Brain-derived Neurotrophic Factor Receptor Signaling Pathway Negative Regulation Of Collateral Sprouting Negative Regulation Of Dendritic Spine Development
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first birth ( 27798627) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Coffee consumption ( 31046077) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hand grip strength ( 29691431) Household income (MTAG) ( 31844048) Mental health study participation (completed survey) ( 31263887) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Platelet distribution width ( 27863252) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 28869590) White blood cell count ( 32888494)	Cognitive decline rate in late mild cognitive impairment ( 26252872) Eyebrow thickness ( 26926045) Gout ( 22179738) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Hypertension ( 22384028) Non-response to selective serotonin reuptake inhibitors and depression ( 27622933) Post bronchodilator FEV1 in COPD ( 26634245) Rheumatoid arthritis ( 30891314) Small cell lung carcinoma ( 28604730) Triglyceride levels ( 32154731 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		16 interacting genes: CBX8 CDCA7L CSNK2A1 FBXO7 GAS2L2 GORASP2 H3-4 ING4 ING5 MEAF6 PACSIN1 SASH1 ZBTB3 ZBTB5 ZNF417 ZNF496
Entrez ID		23338	23105
HPRD ID		15124	17022
Ensembl ID		ENSG00000043143	ENSG00000053108
Uniprot IDs		A0A0C4DFT8 B3KPL2 B4DFY8 G3XAA4 Q9NQC1	Q6MZW2
PDB IDs
Enriched GO Terms of Interacting Partners?
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