KAZN and CELA2A

Data Source:
BioGRID (affinity chromatography technology)

		KAZN	CELA2A
Description		kazrin, periplakin interacting protein	chymotrypsin like elastase 2A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Nucleoplasm Cytosol Cytoskeleton Nuclear Speck Desmosome	Extracellular Region Extracellular Space Cytosol Keratohyalin Granule
	Molecular Function	Protein Binding	Endopeptidase Activity Serine-type Endopeptidase Activity Protein Binding Serine Hydrolase Activity
	Biological Process	Cornification	Proteolysis Response To Insulin Regulation Of Insulin Secretion Cornification Regulation Of Platelet Aggregation Insulin Catabolic Process
Pathways		Formation of the cornified envelope	Formation of the cornified envelope
Drugs			2-(2-HYDROXY-CYCLOPENTYL)-PENT-4-ENAL
Diseases
GWAS		Body mass index ( 28552196) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Chronotype ( 30696823) Conotruncal heart defects (inherited effects) ( 28468790) Copper levels ( 26025379) Lean body mass ( 28552196) Logical memory (delayed recall) in Alzheimer's disease dementia ( 29274321) Mercury levels ( 26025379) Moderate-to-late spontaneous preterm birth ( 31194736) Non-response to antidepressants and depression ( 27622933) Polycystic ovary syndrome (reproductive subtype) ( 32574161) Triacylglyceride levels ( 31551469) Urinary albumin-to-creatinine ratio in diabetes ( 31511532) Weight ( 28552196)	Alcoholic chronic pancreatitis ( 28754779) Blood protein levels ( 30072576) Pulse pressure ( 27841878) Systolic blood pressure ( 28135244 27841878 28739976 30578418)
Interacting Genes		12 interacting genes: ARID5A CLVS2 COIL DVL3 LMO2 LZTS1 LZTS2 PPL PSMA1 TNS4 TXN2 USP2
Entrez ID		23254	63036
HPRD ID		11122	06495
Ensembl ID		ENSG00000189337	ENSG00000142615
Uniprot IDs		Q674X7	P08217
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?